Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL003661-03
Application #
6030393
Study Section
Special Emphasis Panel (ZHL1-CSR-Y (F1))
Project Start
1997-07-01
Project End
2002-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Toso, Raffaella; Bernardi, Francesco; Tidd, Theresa et al. (2003) Factor VII mutant V154G models a zymogen-like form of factor VIIa. Biochem J 369:563-71
Toso, Raffaella; Pinotti, Mirko; High, Katherine A et al. (2002) A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates. Biochem J 363:411-6
Pollak, Eleanor S; Lam, Ho-Sun; Russell, J Eric (2002) The G20210A mutation does not affect the stability of prothrombin mRNA in vivo. Blood 100:359-62
Santacroce, Rosa; Ratti, Antonia; Caroli, Francesco et al. (2002) Analysis of clinically relevant single-nucleotide polymorphisms by use of microelectronic array technology. Clin Chem 48:2124-30
Kudaravalli, Rama; Tidd, Theresa; Pinotti, Mirko et al. (2002) Polymorphic changes in the 5' flanking region of factor VII have a combined effect on promoter strength. Thromb Haemost 88:763-7