The proposed K08 Mentored Clinical Scientist Development Award outlines a program of training and health services research studying the impact of depressive disorders outside of the specialty mental health sector. The candidate is an Assistant Professor of Psychiatry and Public Health at Yale University with a clinical background in psychiatry and primary care internal medicine, as well as postdoctoral health services research training. The career award will allow the candidate to successfully conduct the proposed studies and develop a career as an independent researcher through classes in research design, statistics, economics, and organizational theory at Yale, and via off-site training with experts in the field. Yale University offers a rich source of resources and faculty and a growing breadth of experience in health services research. The career award mentor, Robert A. Rosenheck MD, is a nationally known health services researcher and director of the Health Services Research and Treatment Outcomes Division for the Yale Department of Psychiatry; the candidate and Dr. Rosenheck have developed a close collaborative relationship. The growing importance of purchasers and primary care providers in determining benefits and delivering care for depression has made it an increasing priority to understand the costs of depression in the workplace and general medical settings. The research program seeks to fill gaps in the previous literature studying the impact of depression in these two areas. The first project will seek to provide a better understanding of the causal mechanisms underlying the association between depression and increased use of general medical services. It will examine the role of health beliefs--a person's perception of his or her medical condition, and of the benefits and barriers to treatment--in mediating the relationship between depression and medical utilization. The second project will use a longitudinal database combining work and health claims data for employees of a major US corporation. This project will compare the impact of depression and three chronic medical illnesses on health costs, absenteeism and job performance ratings both cross-sectionally and over time.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Clinical Investigator Award (CIA) (K08)
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Study Section
Services Research Review Committee (SER)
Program Officer
Gonzales, Junius J
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Emory University
Public Health & Prev Medicine
Schools of Public Health
United States
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Levinson, Carolyn M; Druss, Benjamin G (2005) Health beliefs and depression in a group of elderly high utilizers of medical services. Gen Hosp Psychiatry 27:97-9
Druss, Benjamin G; Miller, Carolyn Levinson; Pincus, Harold Alan et al. (2004) The volume-quality relationship of mental health care: does practice make perfect? Am J Psychiatry 161:2282-6
Druss, Benjamin G; Marcus, Steven C (2004) Use of psychotropic medications before and after Sept. 11, 2001. Am J Psychiatry 161:1377-83
Druss, Benjamin G; Marcus, Steven C; Olfson, Mark et al. (2004) Listening to generic Prozac: winners, losers, and sideliners. Health Aff (Millwood) 23:210-6
Druss, Benjamin G; Marcus, Steven C; Olfson, Mark et al. (2003) Trends in care by nonphysician clinicians in the United States. N Engl J Med 348:130-7
Druss, Benjamin G; Miller, Carolyn L; Rosenheck, Robert A et al. (2002) Mental health care quality under managed care in the United States: a view from the Health Employer Data and Information Set (HEDIS). Am J Psychiatry 159:860-2
Druss, Benjamin G; Rosenheck, Robert A; Desai, Mayur M et al. (2002) Quality of preventive medical care for patients with mental disorders. Med Care 40:129-36
Druss, B G; Bradford, W D; Rosenheck, R A et al. (2001) Quality of medical care and excess mortality in older patients with mental disorders. Arch Gen Psychiatry 58:565-72
Druss, B G; Rohrbaugh, R M; Levinson, C M et al. (2001) Integrated medical care for patients with serious psychiatric illness: a randomized trial. Arch Gen Psychiatry 58:861-8
Druss, B G; Marcus, S C; Olfson, M et al. (2001) Comparing the national economic burden of five chronic conditions. Health Aff (Millwood) 20:233-41

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