Elevated depressive symptoms affect nearly 26 percent of older Mexican Americans, but very few (9.1 percent) receive treatment. Older Mexican Americans have high rates of diabetes (33 percent), hypertension (62 percent) and depressive symptoms, which are risks associated with cerebrovascular disease. High rates of cerebrovascular disease risks and low stroke prevention awareness among Latinos presents a looming public health problem as this large population continues to rapidly grow. Currently little is known about the course and progression of mostly untreated depression, particularly as it relates to cerebrovascular disease in this large and rapidly growing population. The overall goal of the proposed research plan is to develop and refine methods for a longitudinal, population-based study of depression and cerebrovascular disease and their association with cognitive and functional status of older Mexican Americans. The Sacramento Area Latino Study on Aging (SALSA) is a population-based, longitudinal cohort study of 1,789 older Latinos of primarily Mexican descent. SALSA has a representative sample, which makes it an especially valuable data source for studying the predictors of cognitive and functional impairment and decline that are associated with depression. The proposed study will address important research questions concerning depression and cerebrovascular disease risk factors among older Mexican Americans, while providing a vehicle for the career development of the candidate.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08MH067726-02
Application #
6731178
Study Section
Social Sciences, Nursing, Epidemiology and Methods 4 (SNEM)
Program Officer
Chavez, Mark
Project Start
2003-04-01
Project End
2008-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
2
Fiscal Year
2004
Total Cost
$147,720
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
González, Hector M; Tarraf, Wassim; Bowen, Mary E et al. (2013) What do parents have to do with my cognitive reserve? Life course perspectives on twelve-year cognitive decline. Neuroepidemiology 41:101-9
American Psychological Association (2012) Guidelines for the evaluation of dementia and age-related cognitive change. Am Psychol 67:1-9
González, Hector M; Tarraf, Wassim; Whitfield, Keith et al. (2012) Vascular depression prevalence and epidemiology in the United States. J Psychiatr Res 46:456-61
Miranda, Patricia Y; Schulz, Amy J; Israel, Barbara A et al. (2011) Context of entry and number of depressive symptoms in an older Mexican-origin immigrant population. J Immigr Minor Health 13:706-12
Bowen, Mary Elizabeth; Gonzalez, Hector M (2010) Childhood socioeconomic position and disability in later life: results of the health and retirement study. Am J Public Health 100 Suppl 1:S197-203
Gonzalez, Hector M; Tarraf, Wassim; West, Brady T et al. (2010) Research article: Antidepressant use among Asians in the United States. Depress Anxiety 27:46-55
González, Hector M; Vega, William A; Tarraf, Wassim (2010) Health care quality perceptions among foreign-born Latinos and the importance of speaking the same language. J Am Board Fam Med 23:745-52
Gonzalez, Hector M; Vega, William A; Williams, David R et al. (2010) Depression care in the United States: too little for too few. Arch Gen Psychiatry 67:37-46
González, Hector M; Tarraf, Wassim; West, Brady T et al. (2009) Antidepressant use in a nationally representative sample of community-dwelling US Latinos with and without depressive and anxiety disorders. Depress Anxiety 26:674-81
Gonzalez, Hector M; Vega, William A; Rodriguez, Michael A et al. (2009) Diabetes awareness and knowledge among Latinos: does a usual source of healthcare matter? J Gen Intern Med 24 Suppl 3:528-33

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