Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08NS001058-05
Application #
3083747
Study Section
Neurological Disorders Program Project Review A Committee (NSPA)
Project Start
1985-12-01
Project End
1990-11-30
Budget Start
1989-12-01
Budget End
1990-11-30
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Olivi, A; Gilbert, M; Duncan, K L et al. (1993) Direct delivery of platinum-based antineoplastics to the central nervous system: a toxicity and ultrastructural study. Cancer Chemother Pharmacol 31:449-54
Tamargo, R J; Myseros, J S; Epstein, J I et al. (1993) Interstitial chemotherapy of the 9L gliosarcoma: controlled release polymers for drug delivery in the brain. Cancer Res 53:329-33
Olivi, A; Donehower, R C; Mann, R B et al. (1991) Solitary, isolated metastasis from Ewing's sarcoma to the brain: case report. Surg Neurol 35:239-43
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Tamargo, R J; Bok, R A; Brem, H (1991) Angiogenesis inhibition by minocycline. Cancer Res 51:672-5
Tamargo, R J; Sills Jr, A K; Reinhard, C S et al. (1991) Interstitial delivery of dexamethasone in the brain for the reduction of peritumoral edema. J Neurosurg 74:956-61
Brem, H (1990) Polymers to treat brain tumours. Biomaterials 11:699-701
Tamargo, R J; Leong, K W; Brem, H (1990) Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate. J Neurooncol 9:131-8
Tamargo, R J; Epstein, J I; Reinhard, C S et al. (1989) Brain biocompatibility of a biodegradable, controlled-release polymer in rats. J Biomed Mater Res 23:253-66
Brem, H; Kader, A; Epstein, J I et al. (1989) Biocompatibility of a biodegradable, controlled-release polymer in the rabbit brain. Sel Cancer Ther 5:55-65

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