Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08NS001766-03
Application #
2036426
Study Section
NST-2 Subcommittee (NST)
Project Start
1994-09-20
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Surgery
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Broaddus, William C; Holloway, Kathryn L; Winters, Charles J et al. (2002) Titanium miniplates or stainless steel wire for cranial fixation: a prospective randomized comparison. J Neurosurg 96:244-7
Chen, Zhi-Jian; Broaddus, William C; Viswanathan, Raju R et al. (2002) Intraparenchymal drug delivery via positive-pressure infusion: experimental and modeling studies of poroelasticity in brain phantom gels. IEEE Trans Biomed Eng 49:85-96
Broaddus, W C; Gillies, G T; Kucharczyk, J (2001) Minimally invasive procedures. Advances in image-guided delivery of drug and cell therapies into the central nervous system. Neuroimaging Clin N Am 11:727-35
Haar, P J; Stewart, J E; Gillies, G T et al. (2001) Quantitative three-dimensional analysis and diffusion modeling of oligonucleotide concentrations after direct intraparenchymal brain infusion. IEEE Trans Biomed Eng 48:560-9
Prabhu, S S; Broaddus, W C; Oveissi, C et al. (2000) Determination of intracranial tumor volumes in a rodent brain using magnetic resonance imaging, Evans blue, and histology: a comparative study. IEEE Trans Biomed Eng 47:259-65
Brust, D; Feden, J; Farnsworth, J et al. (2000) Radiosensitization of rat glioma with bromodeoxycytidine and adenovirus expressing herpes simplex virus-thymidine kinase delivered by slow, rate-controlled positive pressure infusion. Cancer Gene Ther 7:778-88
Fillmore, H L; Shurm, J; Furqueron, P et al. (1999) An in vivo rat model for visualizing glioma tumor cell invasion using stable persistent expression of the green fluorescent protein. Cancer Lett 141:9-19
Prabhu, S S; Broaddus, W C; Gillies, G T et al. (1998) Distribution of macromolecular dyes in brain using positive pressure infusion: a model for direct controlled delivery of therapeutic agents. Surg Neurol 50:367-75;discussion 375
Broaddus, W C; Chen, Z J; Prabhu, S S et al. (1997) Antiproliferative effect of c-myc antisense phosphorothioate oligodeoxynucleotides in malignant glioma cells. Neurosurgery 41:908-15
Mitani, A; Ito, K; Hallanger, A E et al. (1988) Cholinergic projections from the laterodorsal and pedunculopontine tegmental nuclei to the pontine gigantocellular tegmental field in the cat. Brain Res 451:397-402