Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08NS002046-05
Application #
6529058
Study Section
NST-2 Subcommittee (NST)
Program Officer
Fureman, Brandy E
Project Start
1998-07-01
Project End
2003-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
5
Fiscal Year
2002
Total Cost
$126,630
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Gonzalez-Martinez, Jorge A; Ying, Zhong; Prayson, Richard et al. (2011) Glutamate clearance mechanisms in resected cortical dysplasia. J Neurosurg 114:1195-202
Kellinghaus, Christoph; Moddel, Gabriel; Shigeto, Hiroshi et al. (2007) Dissociation between in vitro and in vivo epileptogenicity in a rat model of cortical dysplasia. Epileptic Disord 9:11-9
Najm, Imad M; Tilelli, Cristiane Q; Oghlakian, Roger (2007) Pathophysiological mechanisms of focal cortical dysplasia: a critical review of human tissue studies and animal models. Epilepsia 48 Suppl 2:21-32
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Ying, Zhong; Gonzalez-Martinez, Jorge; Tilelli, Cristiane et al. (2005) Expression of neural stem cell surface marker CD133 in balloon cells of human focal cortical dysplasia. Epilepsia 46:1716-23
Moddel, Gabriel; Jacobson, Berit; Ying, Zhong et al. (2005) The NMDA receptor NR2B subunit contributes to epileptogenesis in human cortical dysplasia. Brain Res 1046:10-23
Palmini, A; Najm, I; Avanzini, G et al. (2004) Terminology and classification of the cortical dysplasias. Neurology 62:S2-8
Kellinghaus, Christoph; Kunieda, Takeharu; Ying, Zhong et al. (2004) Severity of histopathologic abnormalities and in vivo epileptogenicity in the in utero radiation model of rats is dose dependent. Epilepsia 45:583-91
Ying, Zhong; Bingaman, William; Najm, Imad M (2004) Increased numbers of coassembled PSD-95 to NMDA-receptor subunits NR2B and NR1 in human epileptic cortical dysplasia. Epilepsia 45:314-21
Najm, I; Ying, Z; Babb, T et al. (2004) Mechanisms of epileptogenicity in cortical dysplasias. Neurology 62:S9-13

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