Investigation of the role of SMN in Neuronal Apoptosis

Kerr, Douglas A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08NS002130-05
• Application #: 6685224
• Study Section: NST-2 Subcommittee (NST)
• Program Officer: Gwinn, Katrina
• Project Start: 1999-09-30
• Project End: 2004-11-30
• Budget Start: 2003-12-01
• Budget End: 2004-11-30
• Support Year: 5
• Fiscal Year: 2004
• Total Cost: $172,422

Institution

• Name: Johns Hopkins University
• Department: Neurology
• Type: Schools of Medicine
• DUNS #: 001910777
• City: Baltimore
• State: MD
• Country: United States
• Zip Code: 21218

Publications

Darman, Jessica; Backovic, Stephanie; Dike, Sonny et al. (2004) Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity. J Neurosci 24:7566-75

Fannjiang, Yihru; Kim, Chong-Hyun; Huganir, Richard L et al. (2003) BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. Dev Cell 4:575-85

Kerr, Douglas A; Larsen, Thomas; Cook, Susan H et al. (2002) BCL-2 and BAX protect adult mice from lethal Sindbis virus infection but do not protect spinal cord motor neurons or prevent paralysis. J Virol 76:10393-400