Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08NS043517-03
Application #
6529768
Study Section
Subcommittee G - Education (NCI)
Program Officer
Finkelstein, Robert
Project Start
2001-09-30
Project End
2006-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
3
Fiscal Year
2002
Total Cost
$127,815
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Castellino, Robert C; De Bortoli, Massimiliano; Lu, Xiongbin et al. (2008) Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D. J Neurooncol 86:245-56
De Bortoli, Massimiliano; Castellino, Robert C; Skapura, Darlene G et al. (2007) Patched haploinsufficient mouse rhabdomyosarcoma overexpress secreted phosphoprotein 1 and matrix metalloproteinases. Eur J Cancer 43:1308-17
Castellino, Robert C; De Bortoli, Massimiliano; Lin, Linda L et al. (2007) Overexpressed TP73 induces apoptosis in medulloblastoma. BMC Cancer 7:127
De Bortoli, Massimiliano; Castellino, Robert C; Lu, Xin-Yan et al. (2006) Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. BMC Cancer 6:223
Sturla, Lisa-Marie; Cowan, Christopher W; Guenther, Lillian et al. (2005) A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death. Cancer Res 65:5683-9
Kim, John Y H; Nelson, Aaron L; Algon, Sibel A et al. (2003) Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. Dev Biol 263:50-66
Nelson, Aaron L; Algon, Sibel A; Munasinghe, Jeeva et al. (2003) Magnetic resonance imaging of patched heterozygous and xenografted mouse brain tumors. J Neurooncol 62:259-67