Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Physician Scientist Award (K11)
Project #
5K11AI001092-02
Application #
2057127
Study Section
Allergy & Clinical Immunology-1 (AITC)
Project Start
1992-09-01
Project End
2000-08-31
Budget Start
1993-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Duke University
Department
Surgery
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Pruitt, S K; Bollinger, R R; Collins, B H et al. (1997) Effect of continuous complement inhibition using soluble complement receptor type 1 on survival of pig-to-primate cardiac xenografts. Transplantation 63:900-2
Pruitt, S k; Bollinger, R R; Collins, B H et al. (1996) Continuous complement (C) inhibition using soluble C receptor type 1 (sCR1): effect on hyperacute rejection (HAR) of pig-to-primate cardiac xenografts. Transplant Proc 28:756
Pruitt, S K; Baldwin 3rd, W M; Sanfilippo, F (1996) The role of C3a and C5a in hyperacute rejection of guinea pig-to-rat cardiac xenografts. Transplant Proc 28:596
Davis, E A; Pruitt, S K; Greene, P S et al. (1996) Inhibition of complement, evoked antibody, and cellular response prevents rejection of pig-to-primate cardiac xenografts. Transplantation 62:1018-23
Baldwin 3rd, W M; Pruitt, S K; Brauer, R B et al. (1995) Complement in organ transplantation. Contributions to inflammation, injury, and rejection. Transplantation 59:797-808
Pruitt, S K; Baldwin 3rd, W M; Barth, R N et al. (1993) The effect of xenoreactive antibody and B cell depletion on hyperacute rejection of guinea pig-to-rat cardiac xenografts. Transplantation 56:1318-24
Brauer, R B; Baldwin 3rd, W M; Daha, M R et al. (1993) Use of C6-deficient rats to evaluate the mechanism of hyperacute rejection of discordant cardiac xenografts. J Immunol 151:7240-8