In Vivo Selection of Anti-HIV-1 Ribozymes

Campbell, Thomas B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Physician Scientist Award (K11)
• Project #: 5K11AI001159-04
• Application #: 2057251
• Study Section: Acquired Immunodeficiency Syndrome Research Review Committee (AIDS)
• Project Start: 1993-05-01
• Project End: 1998-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Colorado Denver
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 065391526
• City: Aurora
• State: CO
• Country: United States
• Zip Code: 80045

Publications

Campbell, T B; McDonald, C K; Hagen, M (1997) The effect of structure in a long target RNA on ribozyme cleavage efficiency. Nucleic Acids Res 25:4985-93

Campbell, T B; Cech, T R (1996) Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity. Biochemistry 35:11493-502

Campbell, T B; Cech, T R (1995) Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA. RNA 1:598-609

Campbell, T B; Sullenger, B A (1995) Alternative approaches for the application of ribozymes as gene therapies for retroviral infections. Adv Pharmacol 33:143-78