Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Physician Scientist Award (K11)
Project #
5K11DE000363-03
Application #
2128824
Study Section
NIDCR Special Grants Review Committee (DSR)
Project Start
1993-12-15
Project End
1998-12-14
Budget Start
1995-12-15
Budget End
1996-12-14
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
State University New York Stony Brook
Department
Dentistry
Type
Schools of Dentistry
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794

  Publications

Ryan, M E; Usman, A; Ramamurthy, N S et al. (2001) Excessive matrix metalloproteinase activity in diabetes: inhibition by tetracycline analogues with zinc reactivity. Curr Med Chem 8:305-16
Ryan, M E; Ramamurthy, N S; Sorsa, T et al. (1999) MMP-mediated events in diabetes. Ann N Y Acad Sci 878:311-34
Golub, L M; Lee, H M; Ryan, M E et al. (1998) Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms. Adv Dent Res 12:12-26
Ryan, M E; Ramamurthy, N S; Golub, L M (1998) Tetracyclines inhibit protein glycation in experimental diabetes. Adv Dent Res 12:152-8
Golub, L M; Lee, H M; Greenwald, R A et al. (1997) A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis. Inflamm Res 46:310-9
Ryan, M E; Greenwald, R A; Golub, L M (1996) Potential of tetracyclines to modify cartilage breakdown in osteoarthritis. Curr Opin Rheumatol 8:238-47
Ryan, M E; Ramamurthy, S; Golub, L M (1996) Matrix metalloproteinases and their inhibition in periodontal treatment. Curr Opin Periodontol 3:85-96