Project Start
1989-10-01
Project End
1992-06-30
Budget Start
1989-10-01
Budget End
1990-06-30
Support Year
4
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Sacks, D B; Davis, H W; Crimmins, D L et al. (1992) Casein kinase II-catalysed phosphorylation of calmodulin is altered by amino acid deletions in the central helix of calmodulin. Biochem Biophys Res Commun 188:754-9
Sacks, D B; Davis, H W; Williams, J P et al. (1992) Phosphorylation by casein kinase II alters the biological activity of calmodulin. Biochem J 283 ( Pt 1):21-4
Reddy, G P; Reed, W C; Sheehan, E et al. (1992) Calmodulin-specific monoclonal antibodies inhibit DNA replication in mammalian cells. Biochemistry 31:10426-30
Sacks, D B; McDonald, J M (1992) Effects of cationic polypeptides on the activity, substrate interaction, and autophosphorylation of casein kinase II: a study with calmodulin. Arch Biochem Biophys 299:275-80
Sacks, D B; Davis, H W; Crimmins, D L et al. (1992) Insulin-stimulated phosphorylation of calmodulin. Biochem J 286 ( Pt 1):211-6
Sacks, D B; Porter, S E; Ladenson, J H et al. (1991) Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies. Anal Biochem 194:369-77
Sacks, D B; Glenn, K C; McDonald, J M (1989) The carboxyl terminal segment of the c-Ki-ras 2 gene product mediates insulin-stimulated phosphorylation of calmodulin and stimulates insulin-independent autophosphorylation of the insulin receptor. Biochem Biophys Res Commun 161:399-405
Sacks, D B; McDonald, J M (1989) Calmodulin as substrate for insulin-receptor kinase. Phosphorylation by receptors from rat skeletal muscle. Diabetes 38:84-90
Sacks, D B; Fujita-Yamaguchi, Y; Gale, R D et al. (1989) Tyrosine-specific phosphorylation of calmodulin by the insulin receptor kinase purified from human placenta. Biochem J 263:803-12
Fujita-Yamaguchi, Y; Sacks, D B; McDonald, J M et al. (1989) Effect of basic polycations and proteins on purified insulin receptor. Insulin-independent activation of the receptor tyrosine-specific protein kinase by poly(L-lysine). Biochem J 263:813-22

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