Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Physician Scientist Award (K11)
Project #
7K11HL002555-05
Application #
2210169
Study Section
Special Emphasis Panel (SRC (OP))
Project Start
1991-01-01
Project End
1995-12-31
Budget Start
1995-01-01
Budget End
1995-12-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
J. David Gladstone Institutes
Department
Type
DUNS #
047120084
City
San Francisco
State
CA
Country
United States
Zip Code
94158
Coward, P; Wada, H G; Falk, M S et al. (1998) Controlling signaling with a specifically designed Gi-coupled receptor. Proc Natl Acad Sci U S A 95:352-7
Conklin, B R; Herzmark, P; Ishida, S et al. (1996) Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation. Mol Pharmacol 50:885-90
Chabre, O; Conklin, B R; Brandon, S et al. (1994) Coupling of the alpha 2A-adrenergic receptor to multiple G-proteins. A simple approach for estimating receptor-G-protein coupling efficiency in a transient expression system. J Biol Chem 269:5730-4
Lustig, K D; Conklin, B R; Herzmark, P et al. (1993) Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq. J Biol Chem 268:13900-5
Conklin, B R; Chabre, O; Wong, Y H et al. (1992) Recombinant Gq alpha. Mutational activation and coupling to receptors and phospholipase C. J Biol Chem 267:31-4
Chabre, O; Conklin, B R; Lin, H Y et al. (1992) A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways. Mol Endocrinol 6:551-6