The goal of the proposed Postdoctoral Research, Instruction, and Mentorship Experiences (PRIME) IRACDA program is to develop highly skilled biomedical scientists to teach the next generation of clinical researchers and allied health professionals, as well as to promote research competencies of under-represented minority undergraduate and graduate scholars in the health professions. Wake Forest University School of Medicine (WFSM) and Winston-Salem State University (WSSU), an HBCU with longstanding commitment to biomedical and allied health training programs will train PRIME scholars by integrating traditional mentored postdoctoral research at WFSM, regular in-depth professional development programming at WFSM, WFU and WSSU, and a broad variety of teaching assignments in pre-professional and allied health professional (with a focus on Physical Therapy) courses at WSSU. PRIME will aid in recruitment, retention, and development of more underrepresented minority clinical scientists by immersing PRIME scholars, their WFU mentors, and undergraduates in the MARC U*STAR and MBRS RISE programs at WSSU in a rich collaborative learning environment. Additionally, PRIME will strengthen existing collaborations in research and teaching between WFSM and WSSU. To meet these goals, the PRIME Program aims are to: 1. Train scholars in research with a faculty member in WFU's programs in Integrative Physiology and Pharmacology, Neuroscience, Molecular Medicine and Translational Sciences, or Molecular Pathology. 2. Train scholars in mentored teaching experiences at WSSU for the entire three year training, including tutoring, lecturing, laboratory design and development, guiding students through robotics simulations, leading case-based learning (PBL), and open-source digital teaching tools. 3. Introduce PRIME scholars to current pedagogical techniques and educational philosophy through a semester-long course, and short workshops from the WFU Teaching and Learning Center and others. 4. Facilitate mentoring skills by pairing PRIME scholars with WFSM faculty to oversee the research training of WSSU MARC U*STAR and MBRS-RISE undergraduates, and PREP postbac students. 5. Train PRIME scholars in translational research practices (WSSU DPT) and grant writing (WFSM). 6. Train PRIME scholars to become leaders in Responsible Conduct of Research (RCR) education programs. We will recruit 3 PRIME scholars each year for 3 years (a total of 9) from a national pool of racial and ethnically diverse individuals who hold the Ph.D., M.D. or comparable degree. Outcomes of the program will be documented as academic progress in both research and teaching (presentations, publications, meritorious activities), as well as benefits to partner WSSU (improved outcome measures for students~ sustained course modules digitally captured for plug-and-play use). Strategic Evaluations, Inc. is the external evaluation team.

Public Health Relevance

The Sullivan Report (2004) reveals that a major impediment to health equity in the US is the paucity of underrepresented minorities (URM) in the medical and allied health professions. The partnership of Wake Forest University School of Medicine (WFSM) and Winston-Salem State University (WSSU) will contribute to overcoming this disparity by training translational scientists as medical educators for the health professions in western North Carolina, a region populated by rural African American families (17% of North Carolinians) and the fastest growing Hispanic American population in the country (>600% increase in the last decade). By recruiting from a diverse population of applicants, we will increase the numbers of URM academic researchers, and train them to utilize innovative methods that enhance the learning environment and support the career development of URM pre-professional and allied health professions students.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12GM102773-03
Application #
8883209
Study Section
Training and Workforce Development Subcommittee - D (TWD)
Program Officer
Faupel-Badger, Jessica
Project Start
2013-09-01
Project End
2016-06-30
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
3
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Physiology
Type
Schools of Medicine
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157
Diaz-Garelli, Jose-Franck; Wells, Brian J; Yelton, Caleb et al. (2018) Biopsy Records Do Not Reduce Diagnosis Variability in Cancer Patient EHRs: Are We More Uncertain After Knowing? AMIA Jt Summits Transl Sci Proc 2017:72-80
Nickkholgh, Bita; Sittadjody, Sivanandane; Rothberg, Michael B et al. (2017) Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through MYC/MAX transcription complex in prostate cancer. Oncotarget 8:78811-78824
Eldeeb, Khalil; Leone-Kabler, Sandra; Howlett, Allyn C (2017) Mouse Neuroblastoma CB1 Cannabinoid Receptor-Stimulated [35S]GTP?S Binding: Total and Antibody-Targeted G? Protein-Specific Scintillation Proximity Assays. Methods Enzymol 593:1-21
Collett, Jason A; Corridon, Peter R; Mehrotra, Purvi et al. (2017) Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys. J Am Soc Nephrol 28:2081-2092
Blume, Lawrence C; Patten, Theresa; Eldeeb, Khalil et al. (2017) Cannabinoid Receptor Interacting Protein 1a Competition with ?-Arrestin for CB1 Receptor Binding Sites. Mol Pharmacol 91:75-86
Wilson, Bryan A; Cruz-Diaz, Nildris; Su, Yixin et al. (2017) Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake. Am J Physiol Renal Physiol 312:F879-F886
Eldeeb, Khalil; Leone-Kabler, Sandra; Howlett, Allyn C (2016) CB1 cannabinoid receptor-mediated increases in cyclic AMP accumulation are correlated with reduced Gi/o function. J Basic Clin Physiol Pharmacol 27:311-22
Gwathmey, TanYa M; Tallant, E Ann; Howlett, Allyn C et al. (2016) Programs to Recruit and Retain a More Diverse Workforce in Biomedical Sciences Research. J Best Pract Health Prof Divers 9:1188-1194
Cruz-Diaz, Nildris; Wilson, Bryan A; Pirro, Nancy T et al. (2016) Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells. Peptides 83:29-37
Cruz, Nildris; Miranda, Jorge D; Crespo, Maria J (2016) Modulation of Vascular ACE by Oxidative Stress in Young Syrian Cardiomyopathic Hamsters: Therapeutic Implications. J Clin Med 5:

Showing the most recent 10 out of 22 publications