This application proposes to establish a multidisciplinary clinical research program that will prepare clinician scientists for academic leadership and independent research careers in emergency medicine (EM). It draws on well-established collaborations between the Oregon Health &Science University (OHSU) Department of Emergency Medicine (DEM);OHSU's Center for Policy and Research in Emergency Medicine (CPR-EM);the Oregon Clinical and Translational Research Institute (OCTRI, funded by one of the original Clinical and Translational Science Awards in 2006);the Department of Medicine Divisions of Cardiovascular Medicine, Pulmonary &Critical Care Medicine, and Hematology &Medical Oncology;the Department of Surgery Division of Trauma, Critical Care, &Acute Care Surgery;the Department of Pediatrics;the Department of Medical Informatics &Clinical Epidemiology;the Department of Public Health &Preventive Medicine;and the Department of Biomedical Engineering. Furthermore, it initiates or enhances collaborations with the Department of Anesthesiology &Perioperative Medicine;the Department of Physiology &Pharmacology;and the Department of Behavioral Neuroscience within the School of Medicine. It strengthens ties with OHSU's School of Nursing and College of Pharmacy. The primary aim is to produce highly qualified EM researchers, all of whom will have expertise in research fundamentals and the skills required for success as academic physicians and leaders. Each scholar will have developed an area of content expertise for his or her research, along with the specific research skills appropriate to that research topic. By the end of the training period, each scholar will be well-prepared to serve as an independent clinical researcher.
The Specific Aims of the Oregon Multidisciplinary Training Program for Emergency Medicine Clinical Research are 7 To create the next generation of well-trained clinician scientists in the art and science of translational emergency medicine research; 7 To train a diverse group of scholars, with different areas of content expertise reflecting a broad range of cardiovascular, pulmonary, hematological and traumatic emergencies; 7 To produce scholars whose research varies along the spectrum of translational research - from bench- to-bedside to clinical trials - and who have sufficient understanding of comparative effectiveness and health services research to collaborate on multidisciplinary teams that apply scholars'clinical research to broader populations;and 7 To expand the horizon of emergency medicine research by assembling multidisciplinary teams of scientists from a broad range of clinical and basic science disciplines.

Public Health Relevance

ED care is a major component of the US healthcare system and cardiovascular, pulmonary, hematologic and traumatic emergencies are a major component of emergency department utilization - reflecting the heavy burden of these illnesses in the US population. However, treatment of emergency medical and traumatic conditions is often handicapped by lack of evidence-based therapies, and several authorities have identified the limited number of skilled emergency care researchers as a major contributor to this problem. This application proposes to establish a multidisciplinary clinical research program that will prepare clinician- scientists for independent research careers in Emergency Medicine.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HL108974-04
Application #
8715387
Study Section
Special Emphasis Panel (ZHL1-CSR-J (M2))
Program Officer
Scott, Jane
Project Start
2011-07-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
$1,218,316
Indirect Cost
$76,912
Name
Oregon Health and Science University
Department
Emergency Medicine
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Kea, Bory; Lin, Amber L; Olshansky, Brian et al. (2018) Stroke Prophylaxis After a New Emergency Department Diagnosis of Atrial Fibrillation. J Am Coll Cardiol 72:471-472
Duby, Rebecca; Hansen, Matt; Meckler, Garth et al. (2018) Safety Events in High Risk Prehospital Neonatal Calls. Prehosp Emerg Care 22:34-40
Hinson, Holly E; Rowell, Susan; Morris, Cynthia et al. (2018) Early fever after trauma: Does it matter? J Trauma Acute Care Surg 84:19-24
Condron, Mary; Rowell, Susan; Dewey, Elizabeth et al. (2018) The procoagulant molecule plasminogen activator inhibitor-1 is associated with injury severity and shock in patients with and without traumatic brain injury. J Trauma Acute Care Surg 85:888-893
Chang, Anna Marie; Cohen, Deborah J; Lin, Amber et al. (2018) Hospital Strategies for Reducing Emergency Department Crowding: A Mixed-Methods Study. Ann Emerg Med 71:497-505.e4
Rao, Abigail J; Lin, Amber Laurie; Hilliard, Cole et al. (2018) Blood Ethanol Levels Are Not Related to Coagulation Changes, as Measured by Thromboelastography, in Traumatic Brain Injury Patients. World Neurosurg 112:e216-e222
Hansen, Matthew; Schmicker, Robert H; Newgard, Craig D et al. (2018) Time to Epinephrine Administration and Survival From Nonshockable Out-of-Hospital Cardiac Arrest Among Children and Adults. Circulation 137:2032-2040
Guise, Jeanne-Marie; Hansen, Matthew; O'Brien, Kerth et al. (2017) Emergency medical services responders' perceptions of the effect of stress and anxiety on patient safety in the out-of-hospital emergency care of children: a qualitative study. BMJ Open 7:e014057
Menchine, Michael; Kea, Bory (2017) Opioid Prescribing by Emergency Physicians and Risk of Long-Term Use. N Engl J Med 376:1895
Hansen, Matthew L; Lin, Amber; Eriksson, Carl et al. (2017) A comparison of pediatric airway management techniques during out-of-hospital cardiac arrest using the CARES database. Resuscitation 120:51-56

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