Remarkable advances in the diagnosis and management of acute, life-threatening cardiopulmonary and hematologic disorders have occurred in past decades. However, there is growing national concern that expert emergency medicine clinical investigators who can translate new research findings to practice are insufficient in number. It has never been more important to create and maintain a cadre of emergency care physician- scientists, given the unprecedented developments at the cellular and molecular level, including knowledge of the human genome. Innovation in selection, training and career development of new investigators is greatly needed. Vanderbilt University has an extremely successful history in developing well trained researchers who have the vision and skills to embark on successful careers in clinical research. A new career development program, the """"""""Vanderbilt Emergency Medicine Scholars Program"""""""" will focus on training and mentoring physician-scientists in all aspects of research necessary to prepare them for the unique challenges associated with translating basic science into care improvements for acutely ill or injured patients. Although clinically oriented, the program will also highlight the importance of collaborating with basic researchers in hypothesizing and designing clinical research. Two new clinician-scientists who have completed residency (or clinicians with PhDs or equivalent training) and who show exceptional aptitude for successfully pursuing an academic research career will be accepted per year. A total of six Scholars will participate at any one time. The program will concentrate on developing expertise in four focus areas: 1) acute lung injury, 2) asthma, 3) arrhythmias, and 4) acute coronary syndromes and heart failure. These are areas of national recognition and presence for Vanderbilt, and will be bolstered by rich institutional strengths in biomedical informatics, comparative effectiveness, pharmacogenomics, our existing emergency medicine research infrastructure, and continual attraction of a deep, diverse candidate pool. The Program Directors, Douglas B. Sawyer, MD and Alan B. Storrow, MD, have assembled a team of experts in each focus area who are currently engaged in successful academic research and who have devoted their careers to training and mentoring new investigators;both early (Mentors-in-Training) and more senior investigators (Primary Research Mentors) will combine with experts in career development (Academic Mentors) to support Scholars on their paths to independence and contribution to improved diagnosis and management of emergencies.

Public Health Relevance

While incredible advances in the care of acutely ill an injured patients have occurred in past decades, there is growing national concern that expert emergency medicine clinical investigators who can translate new research findings to practice are insufficient in number. We propose a career development program to train a new generation of scientists to address the compelling public health challenges in the management of acute heart, lung, blood, and traumatic diseases.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Physician Scientist Award (Program) (PSA) (K12)
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Special Emphasis Panel (ZHL1-CSR-J (M2))
Program Officer
Scott, Jane
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Vanderbilt University Medical Center
Emergency Medicine
Schools of Medicine
United States
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Huston, Jessica H; Ferre, Robinson; Pang, Peter S et al. (2018) Optimal Endpoints of Acute Heart Failure Therapy. Am J Ther 25:e465-e474
York, Michelle K; Gupta, Deepak K; Reynolds, Cassandra F et al. (2018) B-Type Natriuretic Peptide Levels and Mortality in Patients With and Without Heart Failure. J Am Coll Cardiol 71:2079-2088
Yiadom, Maame Yaa A B; Domenico, Henry; Byrne, Daniel et al. (2018) Randomised controlled pragmatic clinical trial evaluating the effectiveness of a discharge follow-up phone call on 30-day hospital readmissions: balancing pragmatic and explanatory design considerations. BMJ Open 8:e019600
Han, Jin H; Hayhurst, Christina J; Chandrasekhar, Rameela et al. (2018) Delirium's Arousal Subtypes and Their Relationship with 6-Month Functional Status and Cognition. Psychosomatics :
Yiadom, Maame Yaa A B; Baugh, Christopher W; Barrett, Tyler W et al. (2018) Measuring Emergency Department Acuity. Acad Emerg Med 25:65-75
McNaughton, Candace D; Brown, Nancy J; Rothman, Russell L et al. (2017) Systolic Blood Pressure and Biochemical Assessment of Adherence: A Cross-Sectional Analysis in the Emergency Department. Hypertension 70:307-314
Yiadom, Maame Yaa A B; Baugh, Christopher W; Jenkins, Cathy A et al. (2017) Change in Care Transition Practice for Patients With Nonspecific Chest Pain After Emergency Department Evaluation 2006 to 2012. Acad Emerg Med 24:1527-1530
Yiadom, Maame Yaa A B; Liu, Xulei; McWade, Conor M et al. (2017) Acute Coronary Syndrome Screening and Diagnostic Practice Variation. Acad Emerg Med 24:701-709
Han, Jin H; Vasilevskis, Eduard E; Chandrasekhar, Rameela et al. (2017) Delirium in the Emergency Department and Its Extension into Hospitalization (DELINEATE) Study: Effect on 6-month Function and Cognition. J Am Geriatr Soc 65:1333-1338
Fermann, Gregory J; Levy, Phillip D; Pang, Peter et al. (2017) Design and Rationale of a Randomized Trial of a Care Transition Strategy in Patients With Acute Heart Failure Discharged From the Emergency Department: GUIDED-HF (Get With the Guidelines in Emergency Department Patients With Heart Failure). Circ Heart Fail 10:

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