The explosion of medical knowledge and technology contrasts with inefficient and sometimes ineffective health care delivery. Translating scientific advances into better health requires more and better research at several steps leading from bench to practitioner's office and to health systems and communities. We therefore propose a Multidisciplinary K12 Patient- Centered Outcomes Research (PCOR) Training Program at the University of Washington for post-doctoral and entry-level faculty Scholars. This program will support 12 Scholars over a 5- year period.
Our aims are to train investigators who will develop depth in a specific area of PCOR, but also breadth of knowledge about the full spectrum of patient-centered outcomes research; provide them with methodological knowledge and practical skills for conducting high quality integrative research; and create an environment that infuses them with excitement, and nurtures their early career development. The program will involve faculty from the UW Schools of Medicine, Public Health, Pharmacy, and Nursing, as well as prominent affiliated programs such as the Fred Hutchinson Cancer Research Center, Group Health Research Institute and the Puget Sound Veterans Administration Health Services Research and Development unit. Post-doctoral fellows and entry-level faculty Scholars will be recruited nationwide from all health and related professions as well as other disciplines. A multidisciplinary core curriculum will expose all Scholars to the theories and methods of disciplines relevant to PCOR, and elective courses will allow depth of study in a focused area. Intensively mentored research experience will be the centerpiece of the program, and the UW and its Institute for Translational Health Sciences offers an extraordinary range of research cores, centers, and mentors to support this work. We will continuously evaluate program results, and if we are successful, our graduates will become research leaders prepared to conduct multidisciplinary comparative effectiveness research using the highest ethical standards and capitalizing on new technologic and informatics tools.

Public Health Relevance

The issues facing healthcare systems in the United States today are complex and raise questions as to whether we are generating and using evidence of the benefits and harms of medical interventions wisely to improve health across the population. The answers to these questions require rapid, high-quality research that focuses on the needs and outcomes of patients. Our proposed program will train the next generation of Patient-Centered Outcomes Researchers who can efficiently and effectively answer these questions.

Agency
National Institute of Health (NIH)
Institute
Agency for Healthcare Research and Quality (AHRQ)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HS022982-05
Application #
9525084
Study Section
Special Emphasis Panel (ZHS1)
Program Officer
Hsieh, Chinghui
Project Start
2014-08-01
Project End
2019-10-31
Budget Start
2018-08-01
Budget End
2019-10-31
Support Year
5
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Washington
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Marcum, Zachary A; Steinman, Michael A (2018) Developing a Core Outcome Set for Trials to Improve Medication Use: Guidelines or Guidance? J Am Geriatr Soc 66:1058-1059
Adrian, Molly; Lyon, Aaron R; Nicodimos, Semret et al. (2018) Enhanced ""Train and Hope"" for Scalable, Cost-Effective Professional Development in Youth Suicide Prevention. Crisis 39:235-246
Marcum, Zachary A; Walker, Rod; Bobb, Jennifer F et al. (2018) Serum Cholesterol and Incident Alzheimer's Disease: Findings from the Adult Changes in Thought Study. J Am Geriatr Soc 66:2344-2352
Doll, Kemi M; Snyder, Cyndy R; Ford, Chandra L (2018) Endometrial cancer disparities: a race-conscious critique of the literature. Am J Obstet Gynecol 218:474-482.e2
Khandelwal, Nita; Hough, Catherine L; Downey, Lois et al. (2018) Prevalence, Risk Factors, and Outcomes of Financial Stress in Survivors of Critical Illness. Crit Care Med 46:e530-e539
Snyder, Cyndy R; Frogner, Bianca K; Skillman, Susan M (2018) Facilitating Racial and Ethnic Diversity in the Health Workforce. J Allied Health 47:58-65
Zullo, Andrew R; Gray, Shelly L; Holmes, Holly M et al. (2018) Screening for Medication Appropriateness in Older Adults. Clin Geriatr Med 34:39-54
Lee, Sei J; Larson, Eric B; Dublin, Sascha et al. (2018) A Cohort Study of Healthcare Utilization in Older Adults with Undiagnosed Dementia. J Gen Intern Med 33:13-15
Roth, Joshua A; Carter-Harris, Lisa; Brandzel, Susan et al. (2018) A qualitative study exploring patient motivations for screening for lung cancer. PLoS One 13:e0196758
Xie, Jiaheng; Zeng, Daniel Dajun; Marcum, Zachary A (2017) Using deep learning to improve medication safety: the untapped potential of social media. Ther Adv Drug Saf 8:375-377

Showing the most recent 10 out of 32 publications