Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Unknown (K20)
Project #
5K20AA000190-03
Application #
2042896
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1994-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Hill, D B; Barve, S; Joshi-Barve, S et al. (2000) Increased monocyte nuclear factor-kappaB activation and tumor necrosis factor production in alcoholic hepatitis. J Lab Clin Med 135:387-95
Deaciuc, I V; Nikolova-Karakashian, M; Fortunato, F et al. (2000) Apoptosis and dysregulated ceramide metabolism in a murine model of alcohol-enhanced lipopolysaccharide hepatotoxicity. Alcohol Clin Exp Res 24:1557-65
Hill, K K; Hill, D B; Humphries, L L et al. (1999) A role for Helicobacter pylori in the gastrointestinal complaints of eating disorder patients? Int J Eat Disord 25:109-12
Hill, D B; Devalaraja, R; Joshi-Barve, S et al. (1999) Antioxidants attenuate nuclear factor-kappa B activation and tumor necrosis factor-alpha production in alcoholic hepatitis patient monocytes and rat Kupffer cells, in vitro. Clin Biochem 32:563-70
Hill, D B; Awad, J A (1999) Increased urinary F2-isoprostane excretion in alcoholic liver disease. Free Radic Biol Med 26:656-60
Deaciuc, I V; Fortunato, F; D'Souza, N B et al. (1999) Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide. Alcohol Clin Exp Res 23:349-56
McClain, C J; Barve, S; Deaciuc, I et al. (1999) Cytokines in alcoholic liver disease. Semin Liver Dis 19:205-19
McClain, C J; Price, S; Barve, S et al. (1999) Acetaminophen hepatotoxicity: An update. Curr Gastroenterol Rep 1:42-9
Deaciuc, I V; D'Souza, N B; Sarphie, T G et al. (1999) Effects of exogenous superoxide anion and nitric oxide on the scavenging function and electron microscopic appearance of the sinusoidal endothelium in the isolated, perfused rat liver. J Hepatol 30:213-21
Devalaraja, M N; Mcclain, C J; Barve, S et al. (1999) Increased monocyte MCP-1 production in acute alcoholic hepatitis. Cytokine 11:875-81

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