Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Unknown (K20)
Project #
3K20DA000280-03S1
Application #
2656839
Study Section
Special Emphasis Panel (SRCD (03))
Project Start
1995-09-30
Project End
2000-08-31
Budget Start
1997-09-01
Budget End
1998-08-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
City
Torrance
State
CA
Country
United States
Zip Code
90502
Ernst, Thomas; Chang, Linda (2008) Adaptation of brain glutamate plus glutamine during abstinence from chronic methamphetamine use. J Neuroimmune Pharmacol 3:165-72
Chang, Linda; Ernst, Thomas; Speck, Oliver et al. (2005) Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. Am J Psychiatry 162:361-9
Chang, Linda; Ernst, Thomas; St Hillaire, Coryse et al. (2004) Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients. Antivir Ther 9:431-40
Ernst, Thomas; Chang, Linda (2004) Effect of aging on brain metabolism in antiretroviral-naive HIV patients. AIDS 18 Suppl 1:S61-7
Ernst, T; Chang, L; Arnold, S (2003) Increased glial metabolites predict increased working memory network activation in HIV brain injury. Neuroimage 19:1686-93
Ernst, T; Chang, L; Jovicich, J et al. (2002) Abnormal brain activation on functional MRI in cognitively asymptomatic HIV patients. Neurology 59:1343-9
Chang, Linda; Ernst, Thomas; Speck, Oliver et al. (2002) Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users. Psychiatry Res 114:65-79
Goldstein, Rita Z; Volkow, Nora D; Chang, Linda et al. (2002) The orbitofrontal cortex in methamphetamine addiction: involvement in fear. Neuroreport 13:2253-7
Chang, Linda; Ernst, Thomas; Witt, Mallory D et al. (2002) Relationships among brain metabolites, cognitive function, and viral loads in antiretroviral-naive HIV patients. Neuroimage 17:1638-48
Chang, L; Speck, O; Miller, E N et al. (2001) Neural correlates of attention and working memory deficits in HIV patients. Neurology 57:1001-7

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