Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Unknown (K20)
Project #
5K20MH001147-02
Application #
2032826
Study Section
Molecular, Cellular, and Developmental Neurobiology Review Committee (MCDN)
Project Start
1995-09-30
Project End
2000-04-30
Budget Start
1996-09-15
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Kim, E; Arnould, T; Sellin, L K et al. (1999) The polycystic kidney disease 1 gene product modulates Wnt signaling. J Biol Chem 274:4947-53
Kim, E; Arnould, T; Sellin, L et al. (1999) Interaction between RGS7 and polycystin. Proc Natl Acad Sci U S A 96:6371-6
Tsiokas, L; Arnould, T; Zhu, C et al. (1999) Specific association of the gene product of PKD2 with the TRPC1 channel. Proc Natl Acad Sci U S A 96:3934-9
Arnould, T; Sellin, L; Benzing, T et al. (1999) Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2. Mol Cell Biol 19:3423-34
Benzing, T; Brandes, R; Sellin, L et al. (1999) Upregulation of RGS7 may contribute to tumor necrosis factor-induced changes in central nervous function. Nat Med 5:913-8
Gruning, W; Arnould, T; Jochimsen, F et al. (1999) Modulation of renal tubular cell function by RGS3. Am J Physiol 276:F535-43
Arnould, T; Kim, E; Tsiokas, L et al. (1998) The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1. J Biol Chem 273:6013-8
Tsiokas, L; Kim, E; Arnould, T et al. (1997) Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2. Proc Natl Acad Sci U S A 94:6965-70