Molecular Recognition of Antipsychotic Drugs

Javitch, Jonathan A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Mental Health (NIMH)
• Type: Scientist Development Award (K21)
• Project #: 5K21MH001030-05
• Application #: 2240345
• Study Section: Molecular, Cellular, and Developmental Neurobiology Review Committee (MCDN)
• Project Start: 1992-09-30
• Project End: 1997-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: Columbia University (N.Y.)
• Department: Psychiatry
• Type: Schools of Medicine
• DUNS #: 167204994
• City: New York
• State: NY
• Country: United States
• Zip Code: 10032

Publications

Javitch, J A; Fu, D; Chen, J (1996) Differentiating dopamine D2 ligands by their sensitivities to modification of the cysteine exposed in the binding-site crevice. Mol Pharmacol 49:692-8

Javitch, J A; Fu, D; Chen, J (1995) Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice. Biochemistry 34:16433-9

Javitch, J A; Fu, D; Chen, J et al. (1995) Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method. Neuron 14:825-31

Javitch, J A; Li, X; Kaback, J et al. (1994) A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice. Proc Natl Acad Sci U S A 91:10355-9