description): The candidate is interested in how chromatin structure and its nuclear organization into functional domains regulates gene expression in eukaryotic cells, and how this regulation is perturbed in disease states. In yeast Saccharomyces cerevisiae the candidate has identified a cis-acting yeast DNA sequence that acts as a boundary between repressed and active chromatin. A systematic genetic and biochemical analysis of this yeast boundary element will be undertaken to determine the trans-acting protein factors required for its function, and to screen for other yeast DNA sequences possessing boundary activity.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Career Transition Award (K22)
Project #
1K22HD001339-01
Application #
6026989
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Moody, Sally Ann
Project Start
2001-08-06
Project End
2003-07-31
Budget Start
2001-08-06
Budget End
2002-07-31
Support Year
1
Fiscal Year
2001
Total Cost
$133,960
Indirect Cost
Name
Louisiana State University A&M Col Baton Rouge
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
075050765
City
Baton Rouge
State
LA
Country
United States
Zip Code
70803