This award will allow the Principal Investigator, Dr. Conner, to develop expertise in the study of suicide risk-identification in alcoholics. He will develop expertise through collaborative research and research training at the University of Rochester Center for the Study and Prevention of Suicide (CSPS) and education and training in alcoholism research at the Research Institute on Addictions (RIA) in Buffalo, NY. He will also earn a Master's in Public Health degree. Following the award, his goal is to continue programmatic research on the identification of risk factors for suicide in alcoholics, to apply this knowledge in developing community and clinic-based risk-assessment and prevention strategies, and in the long-term to reduce suicide morbidity and mortality in alcoholics. He has chosen to focus on alcoholism, suicide and their association because of their profound public health significance. Alcohol use disorders are the most common psychiatric diagnosis among suicide victims under age 50 but very little is known about the risk factors for suicide in alcoholics. The proposed research is a case-control study of 60 alcohol-dependent suicide victims age 18-49 compared with 60 community controls and 60 clinic controls with alcohol dependence matched for gender, race and age. Cases will be from the population of all suicides in this age group identified over a 3 year period in Monroe County, NY (Rochester) and six surrounding rural counties identified by the Monroe County Medical Examiner. Information about cases and controls will be gathered using comparable methods of informant interviews, structured questionnaires, and record review. The study will test a model for suicide in alcoholism with four foci: aggression, depression, attachment disruption, and alcohol and drug misuse severity. Multiple logistic regression is the principal analytic strategy, with separate analyses for comparisons of suicide victims and clinic controls and community controls respectively.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
5K23AA000318-04
Application #
6647597
Study Section
Special Emphasis Panel (ZAA1-FF (01))
Program Officer
Hough, John F
Project Start
2000-09-14
Project End
2005-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
4
Fiscal Year
2003
Total Cost
$120,530
Indirect Cost
Name
University of Rochester
Department
Psychiatry
Type
Schools of Dentistry
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627
Conner, Kenneth R; Phillips, Michael R; Meldrum, Sean C (2007) Predictors of low-intent and high-intent suicide attempts in rural China. Am J Public Health 97:1842-6
Conner, Kenneth R; Hesselbrock, Victor M; Schuckit, Marc A et al. (2006) Precontemplated and impulsive suicide attempts among individuals with alcohol dependence. J Stud Alcohol 67:95-101
Conner, Kenneth R; Sorensen, Silva; Leonard, Kenneth E (2005) Initial depression and subsequent drinking during alcoholism treatment. J Stud Alcohol 66:401-6
Conner, Kenneth R; Phillips, Michael R; Meldrum, Sean et al. (2005) Low-planned suicides in China. Psychol Med 35:1197-204
Conner, Kenneth R; Conwell, Yeates; Duberstein, Paul R et al. (2004) Aggression in suicide among adults age 50 and over. Am J Geriatr Psychiatry 12:37-42
Conner, Kenneth R (2004) A call for research on planned vs. unplanned suicidal behavior. Suicide Life Threat Behav 34:89-98
Wilcox, Holly C; Conner, Kenneth R; Caine, Eric D (2004) Association of alcohol and drug use disorders and completed suicide: an empirical review of cohort studies. Drug Alcohol Depend 76 Suppl:S11-9
Conner, Kenneth R; Meldrum, Sean; Wieczorek, William F et al. (2004) The association of irritability and impulsivity with suicidal ideation among 15- to 20-year-old males. Suicide Life Threat Behav 34:363-73
Conner, Kenneth R; Duberstein, Paul R (2004) Predisposing and precipitating factors for suicide among alcoholics: empirical review and conceptual integration. Alcohol Clin Exp Res 28:6S-17S
Conner, Kenneth R; Zhong, Yueying; Duberstein, Paul R (2004) NEO-PI-R neuroticism scores in substance-dependent outpatients: internal consistency and self-partner agreement. J Pers Assess 83:75-7

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