Dr. Mody's primary research interest is epidemiology of nosocomial infections in long-term care and developing effective infection control strategies targeted at reducing these infections with a goal to reduce antimicrobial usage, antimicrobial resistance, and adverse events related to antibiotics. Nosocomial infections and adverse drug events particularly related to antibiotics are common preventable medical problems in nursing homes. Dr. Mody's goal is to develop infection control strategies that are targeted and practical while recognizing staffing, budget and care concerns of older adults in nursing homes. Indwelling devices, especially urinary catheters and feeding tubes, are commonly used and appear to play a key role in the development of urinary tract infections and aspiration pneumonias. Dr. Mody's immediate research goals during the Career Development Program are: 1. To assess the epidemiology of colonization with antibiotic-resistant pathogens associated with commonly used devices (urinary catheters, feeding tubes & intravenous lines) in nursing homes in Southeast Michigan. 2. Quantify infection risk and antimicrobial usage attributed to devices. 3. To assess knowledge, attitudes, opinions, and practices of nursing personnel to existing infection control guidelines to prevent device-related infections 4. Assess the efficacy of a targeted infection control program in reducing infections related to devices incorporating educational needs of healthcare workers in nursing homes. This Career Development Award will serve 3 goals: First, this grant will allow Dr. Mody to build on her previous projects conducted during residency and fellowship focusing on the epidemiology and prevention of infection in older adults. Second, it will provide her with an opportunity to take formal coursework in epidemiology and health services research, which will be instrumental to advancing her research career. Third, it will give me a chance to collaborate with a group of community nursing homes in Southeast Michigan. The primary goal of this collaboration will be to design and conduct further outcomes based research projects focusing on nosocomial infections as adverse events and leading to meaningful strategies to improve quality of care of older adults in institutional setting.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
5K23AG022463-05
Application #
7269887
Study Section
National Institute on Aging Initial Review Group (NIA)
Program Officer
Nayfield, Susan G
Project Start
2003-09-30
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2009-08-31
Support Year
5
Fiscal Year
2007
Total Cost
$149,850
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Ismail, Miriam D; Luo, Ting; McNamara, Sara et al. (2016) Long-Term Carriage of Ciprofloxacin-Resistant Escherichia coli Isolates in High-Risk Nursing Home Residents. Infect Control Hosp Epidemiol 37:440-7
Min, Lillian; Galecki, Andrzej; Mody, Lona (2015) Functional disability and nursing resource use are predictive of antimicrobial resistance in nursing homes. J Am Geriatr Soc 63:659-66
Lum, Hillary D; Mody, Lona; Levy, Cari R et al. (2014) Pandemic influenza plans in residential care facilities. J Am Geriatr Soc 62:1310-6
Wang, L; Lansing, B; Symons, K et al. (2012) Infection rate and colonization with antibiotic-resistant organisms in skilled nursing facility residents with indwelling devices. Eur J Clin Microbiol Infect Dis 31:1797-804
Mody, Lona; Bradley, Suzanne (2012) Infection Prevention Research in Nursing Homes. Fed Pract 29:37-40
Fisch, Jay; Lansing, Bonnie; Wang, Linda et al. (2012) New acquisition of antibiotic-resistant organisms in skilled nursing facilities. J Clin Microbiol 50:1698-703
Furuno, Jon P; Krein, Sarah; Lansing, Bonnie et al. (2012) Health care worker opinions on use of isolation precautions in long-term care facilities. Am J Infect Control 40:263-6
Dommeti, Parimala; Wang, Linda; Flannery, Erika L et al. (2011) Patterns of ciprofloxacin-resistant gram-negative bacteria colonization in nursing home residents. Infect Control Hosp Epidemiol 32:177-80
Mody, Lona; Bradley, Suzanne F; Galecki, Andrzej et al. (2011) Conceptual model for reducing infections and antimicrobial resistance in skilled nursing facilities: focusing on residents with indwelling devices. Clin Infect Dis 52:654-61
Mody, Lona; Saint, Sanjay; Galecki, Andrzej et al. (2010) Knowledge of evidence-based urinary catheter care practice recommendations among healthcare workers in nursing homes. J Am Geriatr Soc 58:1532-7

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