The paradox of colorectal cancer (CRC) screening is that healthy older adults are often under-screened and those in poor health are over-screened. One study found that 51% of US adults >75 years with < 10 years of life expectancy were screened while 62% with >10 year LE were not. Guidelines recommend that adults >75 years make individualized decisions based on expectations of benefits, harms, values, and preferences. There is a gap in existing decision aids (DAs) designed for low health literate (LHL) adults >75 years to assist in making CRC screening decisions. This is concerning since risk factors (>75 years, low socioeconomic status, low educational levels, racial/ethnic minority status) for LHL are associated with low CRC knowledge of screening options, low self-efficacy, an apparent lack of desire to participate in SDM, and with less than optimal screening. The primary objective for this K23 application is to optimize CRC screening decisions and improve the quality of care among LHL adults 76-85 years with attention to differences by sex.
The specific aims are to: 1. Identify the information needs and perceptions of LHL older adults about CRC screening; 2. Develop and modify short, paper-based pamphlet CRC DA for use with LHL older adults; and 3. Conduct a feasibility pilot randomized control trial of the CRC DA. Mixed qualitative (structured interviews, focus groups) and quantitative methods will be used to evaluate and test the ?Making a decision about colon cancer screening? DA to create a simple, effective DA tool for use among cognitively intact older adults with LHL in four community based settings and three community health centers. The candidate's long-term goals are to become an independent health services researcher who develops health promotion interventions and improved decision support for underserved and underrepresented older adults with low health literacy. and secure independent research funding through NIH R01's and related awards such as ?Increasing Uptake of Evidence-Based Screening in Diverse Adult Populations (PAR-18-932)? and ?Reducing Overscreening for Breast, Cervical, and Colorectal Cancers among Older Adults; PA-17-109.? To the meet the research objective and career goal, the three training goals are to receive advanced training in:1. Developing skills in health literacy/health communication using mixed methodology; 2. Learning how to develop and evaluate decision support for LHL older adults; and 3. Designing and conducting randomized control trials. The research and career development will take place at Simmons University School of Social Work in collaboration with the Division of General Medicine and Primary Care at Beth Israel Deaconess Medical Center, where the candidate's primary mentor is located. The combination of resources at both institutions provide a very rich intellectual environment with relevant expertise to contribute substantially to the probability of success of the proposed study.

Public Health Relevance

Findings from this study will provide low health literate older adult populations the capability to improve their care and quality of life and consequently be scalable and applicable to educate patients where other health conditions require informed decisions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
5K23AG062795-02
Application #
10084216
Study Section
Neuroscience of Aging Review Committee (NIA)
Program Officer
Salive, Marcel
Project Start
2020-01-15
Project End
2024-12-31
Budget Start
2021-01-01
Budget End
2021-12-31
Support Year
2
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Simmons University
Department
Social Sciences
Type
Schools of Social Welfare/Work
DUNS #
079522819
City
Boston
State
MA
Country
United States
Zip Code
02115