application abstract): The candidate, Dr. Diane Blake, has completed fellowship training in adolescent medicine, with a particular emphasis on sexually transmitted diseases in adolescents. She is now an Assistant Professor at the University of Massachusetts School of Medicine and she proposes a multi-pronged research approach, under the mentorship of Dr. Marianne Felice, (Chair of Pediatrics at the University of Massachusetts), to 1) investigate social and behavioral factors that serve as obstacles to chlamydial screening in adolescent populations; 2) conduct a screening program using urine-based LCR to determine the point prevalence of chlamydia in these two populations and 3) conduct cost effectiveness analysis to determine whether urine-based screening of young people based upon entry into residential setting is cost effective. The project will be phased, involving focus groups that will address issues regarding the knowledge base, perceived barriers, etc. of STD service utilization; construction of a questionnaire that will further explore some of the barriers and ideas for overcoming barriers that were identified in the focus groups; determination of the point prevalence of chlamydia in the populations of these residential settings; followed by analysis of the cost-effectiveness of screening in preventing of sequaelae of untreated chlamydial infections.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
1K23AI001750-01
Application #
6084902
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Savarese, Barbara M
Project Start
2000-09-30
Project End
2005-08-31
Budget Start
2000-09-30
Budget End
2001-08-31
Support Year
1
Fiscal Year
2000
Total Cost
$131,490
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Pediatrics
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Blake, Diane R; Quinn, Thomas C; Gaydos, Charlotte A (2008) Should asymptomatic men be included in chlamydia screening programs? Cost-effectiveness of chlamydia screening among male and female entrants to a national job training program. Sex Transm Dis 35:91-101
Blake, Diane R; Lemay, Celeste A; Indurkhya, Alka (2007) Correlates of readiness to receive Chlamydia screening among 2 populations of youths. Arch Pediatr Adolesc Med 161:1088-94
Blake, Diane R; Doherty, L F (2006) Effect of perineal cleansing on contamination rate of mid-stream urine culture. J Pediatr Adolesc Gynecol 19:31-4
Blake, Diane R; Lemay, Celeste A; Gaydos, Charlotte A et al. (2005) Performance of urine leukocyte esterase in asymptomatic male youth: another look with nucleic acid amplification testing as the gold standard for Chlamydia detection. J Adolesc Health 36:337-41
Blake, Diane R; Gaydos, Charlotte A; Quinn, Thomas C (2004) Cost-effectiveness analysis of screening adolescent males for Chlamydia on admission to detention. Sex Transm Dis 31:85-95
Blake, Diane R; Weber, Brittany M; Fletcher, Kenneth E (2004) Adolescent and young adult women's misunderstanding of the term Pap smear. Arch Pediatr Adolesc Med 158:966-70
Fisher, Lloyd D; Fletcher, Kenneth E; Blake, Diane R (2004) Can the diagnosis of pelvic inflammatory disease be excluded without a bimanual examination? Clin Pediatr (Phila) 43:153-8
Blake, Diane R; Kearney, Margaret H; Oakes, J Michael et al. (2003) Improving participation in Chlamydia screening programs: perspectives of high-risk youth. Arch Pediatr Adolesc Med 157:523-9