The proposed grant will provide for career development and training as well as support for research. The overall goal is to combine research training with my clinical experience to make both experiences more effective and more meaningful. Career development will include formal course work in the basic science underlying auditory event-related potentials (ERPs), including neuroscience, and neuroanatomy & physiology. Mentored career development will include the areas of multi-channel ERPs, including topographic analysis, brain development, ERP maturation, and the responsible conduct of research. Further activities will include travel to respected laboratories in electrophysiology, and attendance at national and international clinical and scientific conferences. (Course work in multivar1ate statistics is not included, as I have had three courses at the doctoral level). The acoustic change complex (ACC) is a cortically generated ERP seen approximately 100 ms after an acoustic change in an ongoing sound. The proposed research will determine whether the ACC can be used as an efficient clinical electrophysiological test of auditory perceptual processing. The major questions to be addressed include: 1) Is the ACC a reliable and stable tool for examining the processing of acoustic change? 2) What is the most efficient means of eliciting the ACC in order to minimize patient testing time and maximize ACC amplitude? 3) Is the ACC reliably elicited in children? If so, how does it change with maturation? 4) Can the ACC be used to predict behavioral discrimination performance in listeners with hearing loss? 5) What are the roles of primary and secondary cortical fields in ACC generation?

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
1K23DC005386-01
Application #
6460290
Study Section
Communication Disorders Review Committee (CDRC)
Program Officer
Sklare, Dan
Project Start
2002-06-01
Project End
2007-04-30
Budget Start
2002-06-01
Budget End
2003-04-30
Support Year
1
Fiscal Year
2002
Total Cost
$151,120
Indirect Cost
Name
Seton Hall University
Department
Other Health Professions
Type
Schools of Allied Health Profes
DUNS #
079324315
City
South Orange
State
NJ
Country
United States
Zip Code
07079
Tan, Chin-Tuan; Martin, Brett A; Svirsky, Mario A (2018) A potential neurophysiological correlate of electric-acoustic pitch matching in adult cochlear implant users: Pilot data. Cochlear Implants Int 19:198-209
Svirsky, Mario A; Fitzgerald, Matthew B; Neuman, Arlene et al. (2012) Current and planned cochlear implant research at New York University Laboratory for Translational Auditory Research. J Am Acad Audiol 23:422-37
Martin, Brett A; Boothroyd, Arthur; Ali, Dassan et al. (2010) Stimulus presentation strategies for eliciting the acoustic change complex: increasing efficiency. Ear Hear 31:356-66
Martin, Brett A; Tremblay, Kelly L; Korczak, Peggy (2008) Speech evoked potentials: from the laboratory to the clinic. Ear Hear 29:285-313
Martin, Brett A (2007) Can the acoustic change complex be recorded in an individual with a cochlear implant? Separating neural responses from cochlear implant artifact. J Am Acad Audiol 18:126-40
Martin, Brett A; Stapells, David R (2005) Effects of low-pass noise masking on auditory event-related potentials to speech. Ear Hear 26:195-213