Overactive bladder (OAB) is defined by the International Continence Society as urinary urgency, with or without urge urinary incontinence, usually with frequency and nocturia. There is a great need for quality-of- care research for women with OAB symptoms. The overall goal of this study is to develop and pilot test a set of indicators of quality of care for women with OAB, emphasizing structure, process, and outcome measures. Dr. Jennifer Anger, MD, MPH, recently completed a NRSA health services research fellowship. She studied the effect of provider variables on outcomes of incontinence surgery for women with stress urinary incontinence. Her proposed career development project and related coursework will greatly expand her research experience into the area of overactive bladder and urge urinary incontinence. The goal of this award period is for Dr. Anger to achieve complete independence as an investigator in urological health services research. She will receive extensive new training with each proposed Specific Aim: 1) To systematically review and summarize the literature on treatment of OAB, incorporating structure/process, and outcomes measures. Training: Systematic literature review 2) To conduct focus groups with patients to understand what information is most needed by women who undergo treatment for OAB symptoms. As part of these focus groups, we will also determine what outcomes matter most to patients with overactive bladder symptoms. Training: Qualitative research methods 3) To conduct interviews with physician experts in incontinence. We will determine what structure, process, and outcomes measures they consider essential to providing excellent quality care for women with OAB. Training: Expert interviews and data analysis 4) To convene an expert consensus panel to develop and rate the list of candidate indicators. Training: The RAND/UCLA Appropriateness Method 5) To pilot test our final set of proposed quality indicators to evaluate their feasibility and sensitivity while simultaneously seeking to identify variation in care between primary care clinics in two healthcare systems. Training: Chart abstraction, methodology, data analysis Relevance: Given the high prevalence and poor cure rate for overactive bladder, improving the quality of care provided to women with OAB through the development of quality-of-care indicators will lead to better patient treatment, and, ultimately, improved patient outcomes.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
Application #
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Rankin, Tracy L
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Schools of Medicine
Los Angeles
United States
Zip Code
Eilber, Karyn S; Alperin, Marianna; Khan, Aqsa et al. (2017) The Role of the Surgeon on Outcomes of Vaginal Prolapse Surgery With Mesh. Female Pelvic Med Reconstr Surg 23:293-296
Anger, Jennifer T; Alas, Alexandriah; Litwin, Mark S et al. (2016) The Quality of Care Provided to Women with Urinary Incontinence in 2 Clinical Settings. J Urol 196:1196-200
Alas, Alexandriah N; Dunivan, Gena C; Wieslander, Cecelia K et al. (2016) Health Care Disparities Among English-Speaking and Spanish-Speaking Women With Pelvic Organ Prolapse at Public and Private Hospitals: What Are the Barriers? Female Pelvic Med Reconstr Surg 22:460-466
Wieslander, Cecilia K; Alas, Alexandriah; Dunivan, Gena C et al. (2015) Misconceptions and miscommunication among Spanish-speaking and English-speaking women with pelvic organ prolapse. Int Urogynecol J 26:597-604
Alas, Alexandriah N; Bresee, Catherine; Eilber, Karyn et al. (2015) Measuring the quality of care provided to women with pelvic organ prolapse. Am J Obstet Gynecol 212:471.e1-9
Khan, Aqsa A; Eilber, Karyn S; Clemens, J Quentin et al. (2015) Trends in management of pelvic organ prolapse among female Medicare beneficiaries. Am J Obstet Gynecol 212:463.e1-8
Qaseem, Amir; Dallas, Paul; Forciea, Mary Ann et al. (2014) Nonsurgical management of urinary incontinence in women: a clinical practice guideline from the American College of Physicians. Ann Intern Med 161:429-40
Anger, Jennifer T; Khan, Aqsa A; Eilber, Karyn S et al. (2014) Short-term outcomes of vaginal mesh placement among female Medicare beneficiaries. Urology 83:768-73
Dunivan, Gena C; Anger, Jennifer T; Alas, Alexandriah et al. (2014) Pelvic organ prolapse: a disease of silence and shame. Female Pelvic Med Reconstr Surg 20:322-7
Bresee, Catherine; Dubina, Emily D; Khan, Aqsa A et al. (2014) Prevalence and correlates of urinary incontinence among older community-dwelling women. Female Pelvic Med Reconstr Surg 20:328-33

Showing the most recent 10 out of 29 publications