This application proposes a training plan to develop Steven L. Mansberger, M.D., M.P.H. into an independent clinician/scientist specializing in ophthalmic epidemiology and biostatistics. Dr. Mansberger is a board certified ophthalmologist with subspecialty training in glaucoma. He has prior research experience involving screening for glaucoma, the relationship between optic disc pathology and visual function, and ocular blood flow. Devers Eye Institute, Oregon Health Science University, and the Northwest Portland Area Indian Health Board have extensive experience with research and education and are especially well suited as training sites. This training program will consist of advanced coursework in biostatistics and epidemiology, multi-disciplinary conferences, and mentored research. Mentored research will be conducted under the direction of a mentorship committee composed of Thomas Becker, M.D., Ph.D., Interim Chairman of the Department of Public Health and Preventive Medicine at OHSU, Chris Johnson, Ph.D., Director of Diagnostic Research at Discoveries In Sight/Devers Eye Institute, and Francine Romero, Ph.D., M.P.H., Principal Investigator of the Northwest Tribal Health Research Center Project. George A. Cioffi, M.D., Anne L. Coleman, M.D., Ph.D., and Dongseok Choi, Ph.D. will serve as consultants on the project as committee members. Most epidemiological studies have used expert personnel, such as ophthalmologists or optometrists, to diagnose eye diseases as part of a prevalence survey. However, newer methods of evaluating the visual field, retina, and optic nerve make it possible for non-MD, non-OD paraprofessionals (such as ophthalmic technicians) to perform a baseline examination and refer participants with abnormal results for a definitive exam by expert personnel. This staged protocol allows persons to be examined rapidly and with reduced expense.
The specific aims of the research project are: 1) to determine if non-MD, non-OD paraprofessionals (such as ophthalmic technicians) performing newer methods of testing have good diagnostic precision and feasibility in comparison to an expert examiner; 2) to attain preliminary data regarding the age-specific prevalence of visual impairment, blindness, and ocular disease in a sample of Northwest American Indians and Alaskan Natives (AI/AN) aged 40 years and older. This project will then lead to a larger, more comprehensive survey of the prevalence and causes of visual impairment in AI/AN.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
5K23EY015501-02
Application #
6895756
Study Section
Special Emphasis Panel (ZEY1-VSN (06))
Program Officer
Everett, Donald F
Project Start
2004-06-01
Project End
2009-05-31
Budget Start
2005-06-01
Budget End
2006-05-31
Support Year
2
Fiscal Year
2005
Total Cost
$237,799
Indirect Cost
Name
Emanuel Hospital and Health Center
Department
Type
DUNS #
050973098
City
Portland
State
OR
Country
United States
Zip Code
97232
Mansberger, Steven L; Sheppler, Christina; Barker, Gordon et al. (2015) Long-term Comparative Effectiveness of Telemedicine in Providing Diabetic Retinopathy Screening Examinations: A Randomized Clinical Trial. JAMA Ophthalmol 133:518-25
Kopplin, Laura J; Mansberger, Steven L (2015) Predictive value of screening tests for visually significant eye disease. Am J Ophthalmol 160:538-546.e3
Mansberger, Steven L; Gleitsmann, Ken; Gardiner, Stuart et al. (2013) Comparing the effectiveness of telemedicine and traditional surveillance in providing diabetic retinopathy screening examinations: a randomized controlled trial. Telemed J E Health 19:942-8
Lloyd, Michael J; Mansberger, Steven L; Fortune, Brad A et al. (2013) Features of optic disc progression in patients with ocular hypertension and early glaucoma. J Glaucoma 22:343-8
Dreer, Laura E; Girkin, Christopher; Mansberger, Steven L (2012) Determinants of medication adherence to topical glaucoma therapy. J Glaucoma 21:234-40
McClure, Tina M; Choi, Dongseok; Wooten, Kathleen et al. (2011) The impact of eyeglasses on vision-related quality of life in American Indian/Alaska Natives. Am J Ophthalmol 151:175-182.e2
Hoffelt, Zakary; Fallon, Shawn; Wong, Brad A et al. (2011) Glaucoma public service announcements: factors associated with follow-up of participants with risk factors for glaucoma. Ophthalmology 118:1327-33
Mansberger, Steven L (2010) Are you compliant with addressing glaucoma adherence? Am J Ophthalmol 149:1-3
Nguyen, H T; Pikey, K P; Gardiner, S K et al. (2009) Intraobserver variability of confocal scanning laser ophthalmoscopy with and without stereo photographs. Br J Ophthalmol 93:1552-3
McClure, Tina M; Choi, Dongseok; Becker, Thomas et al. (2009) The effect of visual impairment on vision-related quality of life in American Indian/Alaska Natives. Ophthalmic Epidemiol 16:128-35

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