This proposal is designed to prepare this applicant, through educational and research experiences, for an independent academic career in the field of child maltreatment research. Dr. Lane will work closely with three mentors at the University of Maryland, Baltimore: Dr. Howard Dubowitz from the Department of Pediatrics, and Drs. Patricia Dischinger and Dr. Patricia Langenberg from the Department of Epidemiology and Preventive Medicine. Dr. Lane plans to enhance her skills in three specific areas: (1) Identification of where prevention interventions are most needed, through an enhanced understanding of risk and protective factors and expanded skills in epidemiology;(2) Knowledge in design and implementation of prevention interventions, including the ethical issues that may arise;(3) Skills in the evaluation of interventions to prevent maltreatment. The didactic portion of this training will include coursework in the design and evaluation of prevention interventions, advanced epidemiology and biostatistics, cost-effectiveness analysis, and responsible conduct of research. The scholar-initiated research will focus on the epidemiology of overt and occult abusive abdominal trauma, as well as child maltreatment prevention.
The specific aims are to: (1) Estimate the incidence of overt and occult abusive abdominal trauma, (2) Compare clinical outcomes of children with abusive abdominal trauma to those with non-abusive abdominal trauma, (3) Identify factors that are associated with a positive screen for occult abdominal trauma among children with suspected abuse, and (4) Determine the cost-effectiveness of a child maltreatment prevention program. Data from several sources will be used. The KID Inpatient Database, a national sample of pediatric hospitalizations, will be used to examine the incidence of overt abusive abdominal trauma. A screening program for occult abdominal trauma will be developed to estimate its incidence among children with suspected abuse. A cost effectiveness analysis will be conducted for Dr. Dubowitz's SEEK III study, which aims to reduce child abuse incidence via risk factor screening in pediatric primary care. In addition to publications, data from this mentored research award will be used to develop independent proposals in child abuse epidemiology and prevention. This proposal has both short- and long-term public health relevance. The specific research projects will help establish evidence-based practice in the medical management and prevention of child abuse. The training component will provide Dr. Lane with the skills to continue this work in future research projects.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Mentored Patient-Oriented Research Career Development Award (K23)
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Special Emphasis Panel (ZHD1-DSR-M (HB))
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Maholmes, Valerie
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University of Maryland Baltimore
Public Health & Prev Medicine
Schools of Medicine
United States
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Sztein, Dina M; Lane, Wendy G (2016) Examination of the Comorbidity of Mental Illness and Somatic Conditions in Hospitalized Children in the United States Using the Kids' Inpatient Database, 2009. Hosp Pediatr 6:126-34
Lane, Wendy Gwirtzman (2014) Prevention of child maltreatment. Pediatr Clin North Am 61:873-88
Lane, Wendy Gwirtzman; Dubowitz, Howard; Feigelman, Susan et al. (2014) The Effectiveness of Food Insecurity Screening in Pediatric Primary Care. Int J Child Health Nutr 3:130-138
Lane, Wendy Gwirtzman; Dubowitz, Howard; Langenberg, Patricia et al. (2012) Epidemiology of abusive abdominal trauma hospitalizations in United States children. Child Abuse Negl 36:142-8
Dubowitz, Howard; Lane, Wendy G; Semiatin, Joshua N et al. (2012) The SEEK model of pediatric primary care: can child maltreatment be prevented in a low-risk population? Acad Pediatr 12:259-68
Dubowitz, Howard; Lane, Wendy G; Semiatin, Joshua N et al. (2011) The safe environment for every kid model: impact on pediatric primary care professionals. Pediatrics 127:e962-70
Lane, Wendy Gwirtzman; Lotwin, Irwin; Dubowitz, Howard et al. (2011) Outcomes for children hospitalized with abusive versus noninflicted abdominal trauma. Pediatrics 127:e1400-5
Feigelman, Susan; Dubowitz, Howard; Lane, Wendy et al. (2011) Training pediatric residents in a primary care clinic to help address psychosocial problems and prevent child maltreatment. Acad Pediatr 11:474-80
Smith, Frances I; Qu, Qiang; Hong, Seok Jong et al. (2005) Gene expression profiling of mouse postnatal cerebellar development using oligonucleotide microarrays designed to detect differences in glycoconjugate expression. Gene Expr Patterns 5:740-9