This application presents a program of research and training that focuses on integrating HIV-prevention strategies into mental health treatments for trauma. Specifically, the proposed project aims to develop and pilot test an intervention for HIV-positive adult survivors of childhood sexual abuse (CSA) who are sexually active and exhibit psychiatric distress related to trauma. The widespread prevalence of CSA among HIV+ adults is concerning as CSA has been linked to poor mental health, substance abuse, HIV risk behavior, and poor treatment adherence and outcome. The training objectives are to develop the PI's expertise in: (1) developing culturally sensitive empirically supported mental health treatments for trauma and CSA, (2) integrating HIV-prevention strategies into mental health treatments for trauma and CSA, and (3) learning advanced quantitative data analytic skills for longitudinal data and outcome analysis. Drs. Kathleen Sikkema and John Briere will supervise the training. The primary goals of the proposed project are to: (1) develop a 16 session individual cognitive-behavioral intervention for HIV+ adults with a history of CSA based on self- trauma theory and tailored to meet the needs of those living with HIV; (2) pilot test this intervention with a sample of 80 participants, 40 who will be randomized into an initial treatment condition followed by a four- month follow-up, and 40 who will be randomized into a four-month waitlist condition followed by treatment with the study intervention; and (3) evaluate the intervention's ability to reduce distress and HIV transmission risk behavior, and collect estimates of effect size for future research. This award will result in a intervention that integrates HIV-prevention strategies into mental health treatment for HIV-positive adults who have experienced CSA, a group with elevated risk for HIV-transmission behavior, that can be evaluated in a randomized, controlled intervention trial. The award will also support the PI's long term goal of integrating HIV-prevention strategies into the mental health care of vulnerable populations, such as survivors of trauma.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Mentored Patient-Oriented Research Career Development Award (K23)
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Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Grossman, Cynthia I
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Yale University
Public Health & Prev Medicine
Schools of Medicine
New Haven
United States
Zip Code
Willie, Tiara C; Kershaw, Trace; Gupta, Jhumka et al. (2018) The Implications of Intimate Partner Violence on Health-Related Quality of Life Among Adults Living With HIV Who Experienced Childhood Sexual Abuse. J Assoc Nurses AIDS Care 29:317-322
Sipsma, Heather; Callands, Tamora A; Bradley, Elizabeth et al. (2013) Healthcare utilisation and empowerment among women in Liberia. J Epidemiol Community Health 67:953-9
Hansen, Nathan B; Harrison, Blair; Fambro, Stacy et al. (2013) The structure of coping among older adults living with HIV/AIDS and depressive symptoms. J Health Psychol 18:198-211
Neufeld, Sharon A S; Sikkema, Kathleen J; Lee, Rachel S et al. (2012) The development and psychometric properties of the HIV and Abuse Related Shame Inventory (HARSI). AIDS Behav 16:1063-74
Hansen, Nathan B; Brown, Lauren J; Tsatkin, Elizabeth et al. (2012) Dissociative experiences during sexual behavior among a sample of adults living with HIV infection and a history of childhood sexual abuse. J Trauma Dissociation 13:345-60
Nightingale, Vienna R; Sher, Tamara G; Mattson, Melissa et al. (2011) The effects of traumatic stressors and HIV-related trauma symptoms on health and health related quality of life. AIDS Behav 15:1870-8
Nightingale, Vienna R; Sher, Tamara G; Thilges, Sarah et al. (2011) Non-conventional practices and immune functioning among individuals receiving conventional care for HIV. J Health Psychol 16:1241-50
Nightingale, Vienna R; Sher, Tamara G; Hansen, Nathan B (2010) The impact of receiving an HIV diagnosis and cognitive processing on psychological distress and posttraumatic growth. J Trauma Stress 23:452-60
Sikkema, Kathleen J; Watt, Melissa H; Drabkin, Anya S et al. (2010) Mental health treatment to reduce HIV transmission risk behavior: a positive prevention model. AIDS Behav 14:252-62
Meade, Christina S; Drabkin, Anya S; Hansen, Nathan B et al. (2010) Reductions in alcohol and cocaine use following a group coping intervention for HIV-positive adults with childhood sexual abuse histories. Addiction 105:1942-51

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