The overall research purpose of this application is to test the feasibility of a multidimensional intervention based on the Information-Motivation-Behavioral Skills (IMB) model to improve treatment adherence for individuals starting on antiretroviral medications for HIV disease. The application also has a training education focus to advance career development through research experience and further education with the support of two outstanding senior investigators. This application will support research and career development by further training in statistics and intervention design in order to conduct the planned intervention study. The proposed intervention to improve adherence uses two individual face-to-face sessions and five telephone calls tapering over a 6-month period to fill informational, motivational, and behavioral deficits assessed prior to the intervention. Innovations include the use of the IMB model as foundation, the inclusion of communication skills training to improve communication with the provider, and the use of a tapering telephone component tailored to the client needs. This research, in a low-income minority population in Southeastern US, is conducted among those who meet the description of the current HIV epidemic in the US. For that reason, this research is significant, in order to reduce health disparities shown by the high levels of mortality from HIV in this population. This feasibility study will provide information and data to support further large-scale research. This training phase will position the candidate to be able to propose an R01 or R03 level investigation, supported by pilot level data derived from the proposed research, and be able to continue her valuable synergy of clinical care and research in unserved populations. Because of the growing interest and commitment to research and faculty development within the University of Mississippi Medical Center (UMMC), as well as her personal commitment to clinical practice with patients with HIV disease, UMMC is an environment that is the most appropriate to support this career development.

National Institute of Health (NIH)
National Institute of Nursing Research (NINR)
Mentored Patient-Oriented Research Career Development Award (K23)
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National Institute of Nursing Research Initial Review Group (NRRC)
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Hare, Martha L
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University of Mississippi Medical Center
Internal Medicine/Medicine
Schools of Medicine
United States
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Konkle-Parker, Deborah J; Erlen, Judith A; Dubbert, Patricia M et al. (2012) Pilot testing of an HIV medication adherence intervention in a public clinic in the Deep South. J Am Acad Nurse Pract 24:488-98
Konkle-Parker, Deborah J; Amico, K Rivet; Henderson, Harold M (2011) Barriers and facilitators to engagement in HIV clinical care in the Deep South: results from semi-structured patient interviews. J Assoc Nurses AIDS Care 22:90-9
Konkle-Parker, Deborah J; Erlen, Judith A; Dubbert, Patricia M (2010) Lessons learned from an HIV adherence pilot study in the Deep South. Patient Educ Couns 78:91-6
Konkle-Parker, Deborah J (2010) How can we facilitate entry into and retention in HIV care? HIV Clin 22:10-1
Amico, K Rivet; Barta, William; Konkle-Parker, Deborah J et al. (2009) The information-motivation-behavioral skills model of ART adherence in a Deep South HIV+ clinic sample. AIDS Behav 13:66-75
Konkle-Parker, Deborah J; Erlen, Judith A; Dubbert, Patricia M (2008) Barriers and facilitators to medication adherence in a southern minority population with HIV disease. J Assoc Nurses AIDS Care 19:98-104
Amico, K Rivet; Konkle-Parker, D J; Cornman, D H et al. (2007) Reasons for ART non-adherence in the Deep South: adherence needs of a sample of HIV-positive patients in Mississippi. AIDS Care 19:1210-8
Konkle-Parker, Deborah (2007) Medication adherence: what are the barriers and facilitators? HIV Clin 19:8-9
Amico, K Rivet; Fisher, William A; Cornman, Deborah H et al. (2006) Visual analog scale of ART adherence: association with 3-day self-report and adherence barriers. J Acquir Immune Defic Syndr 42:455-9