This application supports a renewal of the Midcareer Investigator Award in Patient-Oriented Research from the NIA to Albert L. Siu, M.D., M.S.P.H. Dr. Siu has been at Mount Sinai since 1995 where he has worked within 3 departments (Health Policy, Medicine, and Geriatrics) to build a clinical research program in aging. In November 2002, he became the Chairman of Geriatrics. Over the course of his current award, he has been the primary or secondary mentor to 11 junior investigators who have received 10 career development awards. He is currently active as the primary research mentor to 4 mentees and as the secondary research mentor to 4 ? mentees. Dr. Siu's clinical research in aging focuses on functional status and on the antecedent impairments and disease entities that contribute to poor function. He is proposing mentoring activities that have a focus broader than his personal research interests in recognition of a) the varied interests of potential mentees, b) the considerable overlap between research in functional impairment and in other geriatric clinical syndromes, and c) the importance of engaging the participation of researchers from other clinical disciplines specializing in the impairments and disease entities that contribute to functional impairment and geriatric clinical syndromes.
The specific aims of this application are to: 1) to mentor trainees in geriatrics and other clinical disciplines to conduct patient-oriented research in aging; 2) to use the candidate's and his mentees' ongoing research as a platform to support new mentees and their research; 3) to enhance the infrastructure to support patient-oriented research in aging; and 4) to support pilot studies in patient-oriented research in aging. The proposed mentored patient-oriented research program will provide the mentored investigators with direct research experiences in projects involving the candidate and his mentees. The hands-on research experience will be complemented by 1) classroom experiences matched to the trainee's needs, 2) a weekly lab meeting for clinical research in aging; and 3) less formal sessions that are grounded in adult learning principles to cover a series of topics that collectively might be considered """"""""survival"""""""" skills for clinical researchers in aging. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24AG000918-10
Application #
7431716
Study Section
National Institute on Aging Initial Review Group (NIA)
Program Officer
Nayfield, Susan G
Project Start
1999-06-01
Project End
2010-05-31
Budget Start
2008-06-01
Budget End
2010-05-31
Support Year
10
Fiscal Year
2008
Total Cost
$119,456
Indirect Cost
Name
Icahn School of Medicine at Mount Sinai
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Federman, Alex D; Penrod, Joan D; Livote, Elayne et al. (2010) Development of and recovery from difficulty with activities of daily living: an analysis of national data. J Aging Health 22:1081-98
Morrison, R Sean; Flanagan, Steven; Fischberg, Daniel et al. (2009) A novel interdisciplinary analgesic program reduces pain and improves function in older adults after orthopedic surgery. J Am Geriatr Soc 57:1-10
Penrod, Joan D; Litke, Ann; Hawkes, William G et al. (2008) The association of race, gender, and comorbidity with mortality and function after hip fracture. J Gerontol A Biol Sci Med Sci 63:867-72
Penrod, Joan D; Litke, Ann; Hawkes, William G et al. (2007) Heterogeneity in hip fracture patients: age, functional status, and comorbidity. J Am Geriatr Soc 55:407-13
Siu, Albert L; Boockvar, Kenneth S; Penrod, Joan D et al. (2006) Effect of inpatient quality of care on functional outcomes in patients with hip fracture. Med Care 44:862-9
Federman, Alex D; Halm, Ethan A; Zhu, Carolyn et al. (2006) Association of income and prescription drug coverage with generic medication use among older adults with hypertension. Am J Manag Care 12:611-8
Morrison, R Sean; Meier, Diane E; Fischberg, Daniel et al. (2006) Improving the management of pain in hospitalized adults. Arch Intern Med 166:1033-9
McLaughlin, Mary Ann; Orosz, Gretchen M; Magaziner, Jay et al. (2006) Preoperative status and risk of complications in patients with hip fracture. J Gen Intern Med 21:219-25
Siu, Albert L; Penrod, Joan D; Boockvar, Kenneth S et al. (2006) Early ambulation after hip fracture: effects on function and mortality. Arch Intern Med 166:766-71
Federman, Alex D; Vladeck, Bruce C; Siu, Albert L (2005) Avoidance of health care services because of cost: impact of the medicare savings program. Health Aff (Millwood) 24:263-70

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