Although there has been remarkable progress since the National Academy of Medicine?s report in 2013 describing a path towards Best Care at Lower Cost, we are not where we need to be. My research agenda is to conduct patient-oriented research that advances our understanding of overuse of healthcare among older adults. With the collaboration of junior investigators and other mentees, I will conduct research to understand how health care systems reduce the harmful overuse of healthcare resources by their Medicare beneficiaries through their delivery of high quality primary care. In the last four years of my funded work, my team and I have come to recognize that there is not yet a comprehensive understanding of drivers of overuse at the levels of the patient, clinician, and system, and the most optimal points for interventions are not yet defined. We developed the Johns Hopkins Overuse Index which is an index of 20 procedures that can measure regional variation in the overuse of healthcare resource. The index has been useful as an outcome measure and has allowed us to demonstrate the beneficial impact of higher regional density of primary care doctors on reducing overuse both among Medicare beneficiaries and younger, commercially insured people. I seek to understand the mechanisms by which high quality primary care reduces overuse of resources in older adults through a mixed-methods evaluation of positively deviating health systems and through modeling components of primary care delivery with mediation analysis methods. I also aim to improve the decisions made in the care of older adults by addressing a fundamental problem: that unappreciated heterogeneity of treatment effect (HTE) contributes to overuse of healthcare in older adults. Older adults are at particularly high risk of overuse of healthcare; this is both a discrete subpopulation of all adults, and a population with great variation amongst itself. Contributors to this variation include physiological differences attributable to marked variances in the aging process across individuals that manifests as frailty or robustness, as well as differences that arise due to the degree of multimorbidity, older adults? preferences regarding interventions, and their ability to engage in self-care. The second proposed set of projects will involve the development of methods and tools to help clinicians to communicate more clearly with each other and with patients on this topic. With use of Design Thinking methods and engagement of collaborators from our Department of Art as Applied to Medicine, I will develop a framework and visual tools to assist with clear communication on this topic.

Public Health Relevance

My research agenda is to conduct patient-oriented research that advances understanding of overuse of healthcare among older adults. With the collaboration of junior investigators and other mentees, I will conduct research to understand how health care systems limit the harmful overuse of healthcare resources by their Medicare beneficiaries through their delivery of high quality primary care. The second set of projects involves development of tools to help clinicians to communicate more clearly with patients about heterogeneity of treatment effect in order to reduce the use of healthcare resources in patients unlikely to benefit from their use.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24AG049036-07
Application #
10153604
Study Section
Neuroscience of Aging Review Committee (NIA)
Program Officer
Novak, Priscilla Joy
Project Start
2015-09-01
Project End
2025-02-28
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
7
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Riggs, Kevin R; Bass, Eric B; Segal, Jodi B (2018) Role of Patient- and Surgery-Specific Risk in Receipt of Outpatient Preoperative Testing. Perioper Care Oper Room Manag 10:18-26
Green, Ariel R; Tung, Monica; Segal, Jodi B (2018) Older Adults' Perceptions of the Causes and Consequences of Healthcare Overuse: A Qualitative Study. J Gen Intern Med 33:892-897
Tung, Monica; Sharma, Ritu; Hinson, Jeremiah S et al. (2018) Factors associated with imaging overuse in the emergency department: A systematic review. Am J Emerg Med 36:301-309
Sharma, Ritu; Pannikottu, Jean; Xu, Yunwen et al. (2018) Factors Influencing Overuse of Breast Cancer Screening: A Systematic Review. J Womens Health (Larchmt) 27:1142-1151
Oakes, Allison H; Sharma, Ritu; Jackson, Madeline et al. (2017) Determinants of the overuse of imaging in low-risk prostate cancer: A systematic review. Urol Oncol 35:647-658
Tan, Jingwen; Bae, Sunjae; Segal, Jodi B et al. (2017) Treatment of atrial fibrillation with warfarin among older adults with end stage renal disease. J Nephrol 30:831-839
Green, Ariel R; Segal, Jodi; Tian, Jing et al. (2017) Use of Bladder Antimuscarinics in Older Adults with Impaired Cognition. J Am Geriatr Soc 65:390-394
Nothelle, Stephanie K; Sharma, Ritu; Oakes, Allison H et al. (2017) Determinants of Potentially Inappropriate Medication Use in Long-Term and Acute Care Settings: A Systematic Review. J Am Med Dir Assoc 18:806.e1-806.e17
Tan, Jingwen; Liu, Shuiqing; Segal, Jodi B et al. (2016) Warfarin use and stroke, bleeding and mortality risk in patients with end stage renal disease and atrial fibrillation: a systematic review and meta-analysis. BMC Nephrol 17:157