This K24 renewal application will continue to derive evidence in the field of hand surgery by focusing on the treatment of distal radius fractures (DRF) to teach trainees evidence-based practice and principles. The principal investigator (PI) is a health services researcher whose interests include evidence-based medicine, epidemiology and outcomes research. The PI's previous research has concentrated on musculoskeletal diseases such as rheumatoid arthritis and distal radius fractures (DRF), particularly among the elderly. In addition to continuing research on DRF outcomes, this grant will incorporate a mentoring program to teach evidence-based medicine and research methodology to a growing number of junior faculty, surgery residents, international fellows and medical students. The goal of this project is to initiate a randomized-controlled clinical trial to compare outcomes of two hand therapy programs for elderly patients with DRF, which is the most common injury affecting this growing population. Patients treated with open reduction and internal fixation of DRFs using the volar locking plating system (VLPS) will receive fully-supervised hand therapy (FHT) or minimally supervised self-directed hand therapy (MHT).
The specific aims of the study are (1) To conduct a randomized controlled trial comparing MHT versus traditional FHT for DRFs in the elderly treated with VLPS, and 2) To develop a predictor model to identify patients who will benefit from FHT. The data derived from this study will provide vital information about the postoperative management of this injury and define predictors of functional outcomes after open reduction and internal fixation of DRFs. Furthermore, this study will yield evidence to assist healthcare providers in giving the best care to DRF patients and generate economic data to potentially reduce costs nationally. The principal focus of this K24 award is to apply this project to educate trainees about evidence-based medicine, epidemiology, statistics and study methodology. entire application (candidate, environment, and research). Include the candidate's immediate and long-term career goals, key elements of the research career development plan, and a description of the research project, as indicated in Part I.4.4.6. Provide an abstract of th entire application (candidate, environment, and research). Include the candidate's immediate and long-term career goals, key elements of the research career development plan, and a description of the research project, as indicated in Part I.4.4.6. CC

Public Health Relevance

This K24 renewal application will continue to provide evidence-based research on hand surgery. This grant will investigate the treatment of distal radius fractures and educate trainees in research methodology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24AR053120-10
Application #
9526896
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Washabaugh, Charles H
Project Start
2005-12-01
Project End
2019-05-31
Budget Start
2018-06-01
Budget End
2019-05-31
Support Year
10
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Surgery
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Kelley, Brian P; Kubiak, Carrie; Chung, Kevin C (2018) An On-Top-Plasty Reconstruction for Complicated Radial Polydactyly. Hand (N Y) :1558944717753205
Lark, Meghan E; Kirkpatrick, Kay; Chung, Kevin C (2018) Patient Safety Movement: History and Future Directions. J Hand Surg Am 43:174-178
Cho, Hoyune E; Kelley, Brian; Zhong, Lin et al. (2018) Utilization of Routine Pathology Evaluation of Non-Malignant Lesions in Hand Surgery - A National Study. Plast Reconstr Surg :
Billig, Jessica I; Sterbenz, Jennifer M; Zhong, Lin et al. (2018) Gender Disparities in Preoperative Resource Use for Wrist Arthroscopy. Plast Reconstr Surg 142:1267-1274
Billig, Jessica I; Duncan, Anthony; Zhong, Lin et al. (2018) The Cost of Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer. Plast Reconstr Surg 141:1094-1102
Kamnerdnakta, Sirichai; Huetteman, Helen E; Chung, Kevin C (2018) Use and Associated Spending for Anesthesiologist-Administered Services in Minor Hand Surgery. Plast Reconstr Surg 141:960-969
Harris, Chelsea A; Muller, John-Michael; Shauver, Melissa J et al. (2018) Leveraging the Medical Context to Increase Upper Extremity Reconstruction Among Patients With Tetraplegia: A Qualitative Analysis. Arch Phys Med Rehabil 99:459-467.e1
Kelley, Brian P; Chung, Kevin C; Chung, Ting-Ting et al. (2018) Postoperative Ketorolac in Breast and Body Contouring Procedures: A Nationwide Claims Analysis. Plast Reconstr Surg 142:472e-480e
Yamamoto, Michiro; Chung, Kevin C (2018) Implant Arthroplasty: Selection of Exposure and Implant. Hand Clin 34:195-205
Cho, Hoyune E; Zhong, Lin; Kotsis, Sandra V et al. (2018) Finger Replantation Optimization Study (FRONT): Update on National Trends. J Hand Surg Am 43:903-912.e1

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