Alternative medical methods enjoy broad acceptance by the public, but are rarely integrated into conventional medical practice. In the largest prospective randomized study of its kind, published by the Lancet, the candidate showed that non-pharmacologic analgesia in the form of self- hypnotic relaxation during invasive medical procedures significantly reduces patients' pain anxiety, drug use, number of complications, hemodynamic instability, and procedure time. This results in substantial resource savings. The immediate goal of the candidate is to expand and validate this concept of integrated alternative/conventional health care delivery across disciplines. The long-term goal is the successful transition from scientific investigation to general implementation of acute non-pharmacologic analgesia in clinical settings. The candidate is uniquely situated to achieve the state goals: A strong foundation in laboratory and clinical research as well as her position as Director of International Radiology provides her the necessary credibility to promote and implement mind body intervention during invasive medical procedures. Her acceptance by both conventional medical and mind-body oriented professional societies permit integration of her methods into both communities. The candidate's RO1 and DOD funding focuses on assessment on non-pharmacologic analgesia during invasive vascular procedures and during large core breast biopsy. Under the proposed mid-career award, she will (1) acquire authoritative expertise in the introduction and quality assessment of non- pharmacologic analgesia techniques in conventional clinical settings (2) assume a key role in the newly established Harvard-wide Division for Research and Education and Complementary and Integrative Medical Therapies, and (3) mentor the next generation of researchers and practitioners in this field. Towards these aims the candidate will acquire additional research skills in educational technology, quality assessment, and web-based dissemination; acquire expertise in additional complementary and alternative therapies; and will make available to other researchers data banks, ideas, experience and patients in fully monitored clinical environment. She will assume primary mentoring responsibility for a total of 15 beginning clinical researchers. Upon completion, the candidate will have established herself as an authority in the introduction and quality assessment of combined alternative/conventional medical practices. The mentoring of beginning clinical researchers will have contributed towards fostering a self- sustaining mode of integrated practice in the future.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24AT001074-04
Application #
6881263
Study Section
Special Emphasis Panel (ZAT1-W (01))
Program Officer
Hopp, Craig
Project Start
2002-04-01
Project End
2007-03-31
Budget Start
2005-04-01
Budget End
2006-03-31
Support Year
4
Fiscal Year
2005
Total Cost
$131,475
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
Lang, Elvira V; Tan, Gabriel; Amihai, Ido et al. (2014) Analyzing acute procedural pain in clinical trials. Pain 155:1365-73
Flory, Nicole; Lang, Elvira V (2011) Distress in the radiology waiting room. Radiology 260:166-73
Flory, Nicole; Lang, Elvira (2008) Practical hypnotic interventions during invasive cancer diagnosis and treatment. Hematol Oncol Clin North Am 22:709-25, ix
Lang, Elvira V; Berbaum, Kevin S; Pauker, Stephen G et al. (2008) Beneficial effects of hypnosis and adverse effects of empathic attention during percutaneous tumor treatment: when being nice does not suffice. J Vasc Interv Radiol 19:897-905
Lutgendorf, Susan K; Lang, Elvira V; Berbaum, Kevin S et al. (2007) Effects of age on responsiveness to adjunct hypnotic analgesia during invasive medical procedures. Psychosom Med 69:191-9
Flory, Nicole; Salazar, Gloria M Martinez; Lang, Elvira V (2007) Hypnosis for acute distress management during medical procedures. Int J Clin Exp Hypn 55:303-17
Lang, Elvira V; Berbaum, Kevin S; Faintuch, Salomao et al. (2006) Adjunctive self-hypnotic relaxation for outpatient medical procedures: a prospective randomized trial with women undergoing large core breast biopsy. Pain 126:155-64
Lang, Elvira V; Sood, Ajay; Anderson, Brad et al. (2005) Interpersonal and communication skills training for radiology trainees using a rotating peer supervision model (microteaching). Acad Radiol 12:901-8
Lang, Elvira V; Hatsiopoulou, Olga; Koch, Timo et al. (2005) Can words hurt? Patient-provider interactions during invasive procedures. Pain 114:303-9
Lang, Elvira V; Reyes, Jorge; Faintuch, Salomao et al. (2005) Central venous recanalization in patients with short gut syndrome: restoration of candidacy for intestinal and multivisceral transplantation. J Vasc Interv Radiol 16:1203-13

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