Primary care providers are in position to assist addicted persons by recognizing and diagnosing substance abuse, treating co-existing medical and mental health disorders, directing patients to substance abuse programs as needed, and monitoring care after specialty treatment and recovery. According to Dr. Alan Leshner, """"""""proper diagnosis and treatment for all co-morbid disorders is crucial to successful recovery. The integration of concurrent treatment of both the mental and addictive disorders appears to be the best approach"""""""". The overall goal of the proposed project is to develop, implement and evaluate the efficacy and effectiveness of behavioral interventions for complex drug abusing patients in new treatment settings.
The aims are: 1) to provide scientific and administrative leadership for the group of young investigators, based in a Division of General Internal Medicine Substance Abuse Research Unit, who are interested in these problems; 2) to provide training support for drug abuse treatment and services research, including support for junior faculty. Michael D. Stein, M.D., is Associate Professor of Medicine in the Brown University School of Medicine and Director of Substance Abuse Research Unit in the Division of General Internal Medicine. Dr. Stein also serves as Director of HIV Services at Rhode Island Hospital. His three ongoing R01s study complex substance abusing patients with comorbid conditions, in particular injection drug users. The information provided in this application demonstrates a productive career as a patient-oriented clinical epidemiologist in drug abuse research and Dr. Stein's interest in translating this research to primary care and substance abuse treatment settings while mentoring new clinical investigators.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
Application #
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Denisco, Richard A
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Rhode Island Hospital
United States
Zip Code
Caviness, Celeste M; Anderson, Bradley J; Stein, Michael D (2017) Energy drinks and alcohol-related risk among young adults. Subst Abus 38:376-381
Uebelacker, Lisa A; Bailey, Genie; Herman, Debra et al. (2016) Patients' Beliefs About Medications are Associated with Stated Preference for Methadone, Buprenorphine, Naltrexone, or no Medication-Assisted Therapy Following Inpatient Opioid Detoxification. J Subst Abuse Treat 66:48-53
Stein, Michael D; Risi, Megan M; Bailey, Genie L et al. (2016) Linkage to Primary Care for Persons First Receiving Injectable Naltrexone During Inpatient Opioid Detoxification. J Subst Abuse Treat 64:44-6
Wilder, Christine M; Miller, Shannon C; Tiffany, Elizabeth et al. (2016) Risk factors for opioid overdose and awareness of overdose risk among veterans prescribed chronic opioids for addiction or pain. J Addict Dis 35:42-51
Hayaki, Jumi; Anderson, Bradley J; Stein, Michael D (2016) Dual cannabis and alcohol use disorders in young adults: Problems magnified. Subst Abus 37:579-583
Stein, Michael D; Risi, Megan M; Flori, Jessica N et al. (2016) Gender Differences in the Life Concerns of Persons Seeking Alcohol Detoxification. J Subst Abuse Treat 63:34-8
Stein, Michael D; Caviness, Celeste; Grimone, Kristin et al. (2016) An Open Trial of Electronic Cigarettes for Smoking Cessation Among Methadone-Maintained Smokers. Nicotine Tob Res 18:1157-62
Stein, Michael D; Caviness, Celeste M; Grimone, Kristin et al. (2015) E-cigarette knowledge, attitudes, and use in opioid dependent smokers. J Subst Abuse Treat 52:73-7
Stein, Michael D; Herman, Debra S; Bailey, Genie L et al. (2015) Chronic pain and depression among primary care patients treated with buprenorphine. J Gen Intern Med 30:935-41
Stein, Michael D; Anderson, Bradley J; Bailey, Genie L (2015) Preferences for Aftercare Among Persons Seeking Short-Term Opioid Detoxification. J Subst Abuse Treat 59:99-103

Showing the most recent 10 out of 81 publications