This Mid-Career Investigator Award is designed to support the continued research development and mentoring activities of Stevan Weine MD, Professor of Psychiatry at the University of Illinois at Chicago. Over the past 15 years, Dr. Weine has demonstrated a strong commitment to patient-oriented research and mentoring new investigators. He is a psychiatrist and an established researcher in trauma, migration, and HIV/AIDS impacted families, with continuous federal funding as Principal Investigator since 1998. His overall research mission is to develop, implement, and evaluate psychosocial interventions that are feasible, acceptable, and effective with respect to the complex real-life contexts where migrants and refugees live. Goals for this proposal include: 1) training and mentoring students, trainees, and junior faculty in patient-oriented research generally, and multilevel HIV prevention and refugee and migrant research specifically;2) receiving consultation from senior researchers regarding mixed methods in preventive intervention development, research collaborations with families and communities, and ethics in HIV/AIDS and migration research;3) expanding research activities so as to build the intervention content and methodology needed to develop and evaluate multilevel HIV preventive interventions for labor migrants. The mentoring plan incorporates individual mentoring, mentees direct consultation from the senior mentors, formal courses and seminars, training regarding research ethics, and mentees'direct involvement in a research project. There are three proposed studies that build off an ongoing five year NICHD funded study (5R01MH076118-02) being conducted in Tajikistan and Russia that investigates the social, cultural, and psychological constructions of masculinity and their impact on HIV risk and prevention. Study 1 uses mixed methods to build an evidence base for developing multilevel interventions with labor migrants. Study 2 designs a multilevel HIV preventive intervention for Tajik labor migrants through a community-researcher collaborative. Study 3 pilots components of the multilevel intervention, examines engagement, retention, outcomes, and mediators, and estimates parameters for a future large scale R01 investigation.

Public Health Relevance

Impacting billions globally, labor migration adds to family burdens and instability, changes the social landscape, and is associated with increased HIV risk behaviors. In Russia and Central Asia, where AIDS rates are amongst the world's highest, conditions in both sending and receiving countries pose serious obstacles to HIV prevention. Because Tajikistan is so highly impacted by labor migration and is one of the world's poorest countries, it is at substantial risk for an HIV/AIDS epidemic. To build HIV prevention services for migration- impacted populations calls for understanding how to intervene amongst the complex circumstances of labor migration. This five-year K24 program of mentoring, research, and training consultation is designed to improve HIV preventive services for labor migrants and their families. The research draws upon social science and behavioral methods to develop and partially pilot a multilevel HIV preventive intervention for migration- impacted persons in Tajikistan and Russia. There are three studies for this Midcareer Investigator Award. These studies are designed to build the intervention content and methodology needed to develop and evaluate multilevel interventions for labor migrants. They also provide the basis for mentoring junior investigators.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Midcareer Investigator Award in Patient-Oriented Research (K24)
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Behavioral and Social Science Approaches to Preventing HIV/AIDS Study Section (BSPH)
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Newcomer, Susan
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University of Illinois at Chicago
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Zabrocki, Christopher; Polutnik, Chloe; Jonbekov, Jonbek et al. (2015) Condom use and intimacy among Tajik male migrants and their regular female partners in Moscow. Cult Health Sex 17:17-33
Weine, Stevan Merrill; Ware, Norma; Hakizimana, Leonce et al. (2014) Fostering Resilience: Protective Agents, Resources, and Mechanisms for Adolescent Refugees' Psychosocial Well-Being. Adolesc Psychiatry (Hilversum) 4:164-176
Weine, Stevan Merrill; Ware, Norma; Tugenberg, Toni et al. (2013) Thriving, Managing, and Struggling: A Mixed Methods Study of Adolescent African Refugees' Psychosocial Adjustment. Adolesc Psychiatry (Hilversum) 3:72-81
Weine, Stevan; Bahromov, Mahbat; Loue, Sana et al. (2013) HIV sexual risk behaviors and multilevel determinants among male labor migrants from Tajikistan. J Immigr Minor Health 15:700-10
Zabrocki, Christopher; Weine, Stevan; Chen, Stephanie et al. (2013) Socio-Structural Barriers, Protective Factors, and HIV Risk Among Central-Asian Female Migrants in Moscow. Cent Asian J Glob Health 2:
Weine, Stevan; Golobof, Alexandra; Bahromov, Mahbat et al. (2013) Female migrant sex workers in Moscow: gender and power factors and HIV risk. Women Health 53:56-73
Weine, Stevan M; Kashuba, Adrianna B (2012) Labor migration and HIV risk: a systematic review of the literature. AIDS Behav 16:1605-21
Jing, Luo; Weine, Stevan; Bahromov, Mahbat et al. (2012) Does Powerlessness Explain Elevated HIV Risk Amongst Tajik Labor Migrants? An Ethnographic Study. J HIV AIDS Soc Serv 11:105-124
Weine, Stevan; Bahromov, Mahbat; Loue, Sana et al. (2012) Trauma exposure, PTSD, and HIV sexual risk behaviors among labor migrants from Tajikistan. AIDS Behav 16:1659-69
Bahromov, Mahbat; Weine, Stevan (2011) HIV prevention for migrants in transit: developing and testing TRAIN. AIDS Educ Prev 23:267-80

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