In the 10 years I have been on the UCSF faculty, I have developed an independent program focused on three major areas of interest: 1) Understanding how care systems might be best arranged to improve both quality and outcomes of healthcare, such as how cardiologists or hospitalists might affect outcomes of patients with congestive heart failure;2) Understanding how improve use of beta-blockers in noncardiac surgery as a way to reduce cardiac morbidity, and 3) Improving our ability to measure the quality of healthcare and implement change effectively. My work has placed a particular emphasis on the management of patients with cardiovascular illness who are undergoing major noncardiac surgery as a paradigm for these questions. Over the 5-year K24 award period, my goals are to further develop my research program and mentor investigators who will be passionate about these same areas, and who will become successful independent investigators. To achieve this 5 year goal, this K24 has 2 specific aims: (1) to perform patient-oriented research aimed at understanding how hospitalization for noncardiac surgery produces gaps in cardiac medications and how these gaps affect patient outcomes. I will use local and national data to understand how often cardiovascular medications (for example, use of aspirin in patients with coronary artery disease, or angiotensin-converting enzyme inhibitors in patients with congestive heart failure) are missed or dropped in noncardiac surgery patients, and how discontinuity in these medications impacts patient outcomes. (2) To create a mentorship program that will foster the development of patient-oriented researchers interested in improving the quality of care for patients with cardiovascular disease. I will mentor fellows and junior faculty, and diversify my mentorship portfolio to include a greater emphasis on the development of cardiovascular specialists, hospitalists, and subspecialists who have an interest in quality-improvement (or, translating evidence into practice) research as their career goal.

Public Health Relevance

This proposal is relevant to the mission of NHLBI as it aims to develop understanding of problems that have scientific and policy importance in the care of patients with coronary artery disease and congestive heart failure. Moreover, the mentorship program will develop researchers with a skillset that will be critical during an era which will place even greater priority on translation of evidence into practice.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Midcareer Investigator Award in Patient-Oriented Research (K24)
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Study Section
Special Emphasis Panel (ZHL1-CSR-R (O1))
Program Officer
Carlson, Drew E
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University of California San Francisco
Internal Medicine/Medicine
Schools of Medicine
San Francisco
United States
Zip Code
Rosenbluth, Glenn; Jacolbia, Ronald; Milev, Dimiter et al. (2016) Half-life of a printed handoff document. BMJ Qual Saf 25:324-8
Rajkomar, Alvin; Valencia, Victoria; Novelero, Maria et al. (2016) The association between discharge before noon and length of stay in medical and surgical patients. J Hosp Med 11:859-861
Patel, Hemali; Fang, Margaret C; Harrison, James D et al. (2016) Implementation and evaluation of a ""works-in-progress"" session to promote scholarship in an academic hospitalist group. J Hosp Med 11:719-723
Harrison, James D; Greysen, Ryan S; Jacolbia, Ronald et al. (2016) Not ready, not set…discharge: Patient-reported barriers to discharge readiness at an academic medical center. J Hosp Med 11:610-4
Herzig, Shoshana J; Schnipper, Jeffrey L; Doctoroff, Lauren et al. (2016) Physician Perspectives on Factors Contributing to Readmissions and Potential Prevention Strategies: A Multicenter Survey. J Gen Intern Med 31:1287-1293
Vukkadala, Neelaysh; Auerbach, Andrew; Maselli, Judith H et al. (2016) Association between ordering patterns and shift-based care in general pediatrics inpatients. J Hosp Med 11:210-4
Auerbach, Andrew D; Kripalani, Sunil; Vasilevskis, Eduard E et al. (2016) Preventability and Causes of Readmissions in a National Cohort of General Medicine Patients. JAMA Intern Med 176:484-93
Makam, Anil N; Nguyen, Oanh K; Auerbach, Andrew D (2015) Diagnostic accuracy and effectiveness of automated electronic sepsis alert systems: A systematic review. J Hosp Med 10:396-402
Wattier, Rachel L; Dvorak, Christopher C; Auerbach, Andrew D et al. (2015) Repeat blood cultures in children with persistent fever and neutropenia: Diagnostic and clinical implications. Pediatr Blood Cancer 62:1421-6
Whitlock, Elizabeth L; Kim, Helen; Auerbach, Andrew D (2015) Harms associated with single unit perioperative transfusion: retrospective population based analysis. BMJ 350:h3037

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