Peter K. Lindenauer MD MSc is a hospitalist, Associate Professor of Medicine at the Tufts University School of Medicine and Tufts Clinical and Translational Science Institute, and Director of the Center for Quality of Care Research at Baystate Medical Center. Over the past 7 years he has built a nationally recognized, independent, NIH-funded program in comparative effectiveness research and implementation science focused on the hospital management of patients with Chronic Obstructive Pulmonary Disease (COPD). During this same period he has fostered the academic careers of numerous residents, fellows, and junior faculty who have achieved academic promotion and have developed independent research careers in patient-oriented research. He is the primary mentor to 5 current K awardees, spanning NHLBI, NICHD, AHRQ and Tufts/NCATS, and is a co-mentor to 11 other investigators. His long-term goals are to conduct patient-oriented research to improve the quality of care and outcomes for patients with lung disease, especially during and following hospitalization, and to provide mentoring to new investigators with an interest in patient-oriented research.
The aims of this proposal are 1) To continue to build his mentoring skills through formal coursework and supervision by senior mentors, leveraging his role as Director of the Center for Quality of Care Research and member of the core group of CTSI mentors to select promising candidates for training, and to ensure that current mentees successfully transition to K and R awards; 2) To continue to build a research program around improving care for patients hospitalized with exacerbations of COPD.
This aim will be accomplished through his currently funded studies, including an NLHBI R18 entitled Implementation and Outcomes of Noninvasive Ventilation in COPD, and by new research proposed through this award that will use mixed qualitative and quantitative methods to examine the use and effectiveness of Pulmonary Rehabilitation in the early period following hospitalization for COPD. These projects will provide the necessary research infrastructure and opportunities for mentees to develop their own projects under this umbrella. The mentoring program that is proposed selects promising candidates from the fields of general internal medicine, pulmonary and critical care medicine, cardiology, and emergency medicine and provides a structured and rigorous program of research training and career development under Dr. Lindenauer's mentorship. The program is fully integrated with the Tufts CTSI and Sackler School graduate programs in Clinical and Translational Science. In the strongly supportive environment of Baystate Medical Center and the Tufts CTSI, this award will ensure that Dr. Lindenauer can continue to invest the substantial time required to provide high quality mentoring to the next generation of patient-oriented researchers while continuing to build his mentoring skills and research program in lung disease.

Public Health Relevance

COPD affects as many as 24 million individuals in the US and is responsible for more than 800,000 hospitalizations each year, leading to increased morbidity, mortality and costs. The goals of this K24 are to conduct patient-oriented research focused on improving care for patients hospitalized for COPD, and to train new investigators in the fields of comparative effectiveness research and implementation science. The ultimate goal of these activities is to expand research capacity and knowledge in this area, thereby improving care for patients with lung disease.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
Application #
Study Section
NHLBI Mentored Patient-Oriented Research Review Committee (MPOR)
Program Officer
Tigno, Xenia
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Baystate Medical Center
United States
Zip Code
Walkey, Allan J; Shieh, Meng-Shiou; Liu, Vincent X et al. (2018) Mortality Measures to Profile Hospital Performance for Patients With Septic Shock. Crit Care Med 46:1247-1254
Schoenfeld, Elizabeth M; Goff, Sarah L; Downs, Gwendolyn et al. (2018) A Qualitative Analysis of Patients' Perceptions of Shared Decision Making in the Emergency Department: ""Let Me Know I Have a Choice"". Acad Emerg Med 25:716-727
Leyenaar, JoAnna K; Shieh, Meng-Shiou; Lagu, Tara et al. (2018) Hospital and Community Characteristics Associated With Pediatric Direct Admission to Hospital. Acad Pediatr 18:525-534
Johnson, Karin G; Lindenauer, Peter K (2018) Failure of PAP Therapy to Alter the Trajectory of Health Care Utilization Among Patients With OSA: A Wake-up Call for the Field of Sleep Medicine or Just a Bad Dream? Med Care 56:899-900
Leyenaar, JoAnna K; Shevenell, Megan; Rizzo, Paul A et al. (2018) Multi-Stakeholder Informed Guidelines for Direct Admission of Children to Hospital. J Pediatr 198:273-278.e7
Lindenauer, Peter K; Dharmarajan, Kumar; Krumholz, Harlan M (2018) Reply to Soo Hoo and Esquinas: Risk Trajectories of Readmission and Death in the First Year after Hospitalization for Chronic Obstructive Pulmonary Disease: Don't Shortchange Noninvasive Ventilation. Am J Respir Crit Care Med 198:283-284
Ramdass, Sheryl K; Brennan, Maura J; Starr, Rebecca et al. (2018) The Association of Frailty with Discharge Disposition for Hospitalized Community Dwelling Elderly Patients. J Hosp Med 13:182-184
Stefan, Mihaela S; Priya, Aruna; Pekow, Penelope S et al. (2018) The comparative effectiveness of noninvasive and invasive ventilation in patients with pneumonia. J Crit Care 43:190-196
Schoenfeld, Elizabeth M; Goff, Sarah L; Elia, Tala R et al. (2018) A Qualitative Analysis of Attending Physicians' Use of Shared Decision-Making: Implications for Resident Education. J Grad Med Educ 10:43-50
Cohen, David M; Winter, Michael; Lindenauer, Peter K et al. (2018) Echocardiogram in the Evaluation of Hemodynamically Stable Acute Pulmonary Embolism: National Practices and Clinical Outcomes. Ann Am Thorac Soc 15:581-588

Showing the most recent 10 out of 30 publications