Despite explosive gains in our understanding of the basic mechanisms of human disease, meaningful? translation of this knowledge to the treatment ahd prevention of disease has moved slowly. To? accelerate the pace at which discoveries in basic science can serve the health of our patients and? community, we intend to establish a Clinical and Translational Science Institute (CTSI) at trip University? of California, San Francisco (UCSF). Its mission will be to create a comprehensive, integrated? academic home that.promotes research and education in clinical and translational science at UCSF, at? affiliated institutions, and in participating communities. Its goals are: (1) to support, enhance, and? integrate existing training programs, increasing the number of trainees from diverse disciplines and? improving the quality of their training in clinical and translational research methods; (2) to support,? improve, and integrate existing infrastructure to enhance the design and implementation of clinical and? translational studies, fostering collaborations to achieve a diverse spectrum of high quality, original? research; (3) to enhance career development of clinical and translational researchers by providing? mentoring and opportunities to catalyze original research and by changing the academic culture to? appropriately reward multidisciplinary collaborative work; (4)1o create a """"""""Virtual Home"""""""" providing? contemporary communications to simplify collaboration, to provide an optimal informatics matrix for? conducting innovative research, and to nurture the growth of clinical and translational science.? To reach these goals, UCSF is transforming its clinical and translational research organization to? establish 13 interrelated programs that will provide the training, services, and opportunities needed.? These programs are led by senior scientists drawn from diverse disciplines in each of UCSPs four? health science schools?Dentistry, Medicine, Nursing, and Pharmacy?and its Graduate Division. The? plans reflect input from more than 200 interested, energetic, and committed participants from? throughout the community, including most of UCSF's academic leaders. These individuals worked? collaboratively to ensure inclusion, transparency, and flexibility in the design and planned? implementation of the CTSI. A significant financial commitment to the CTSI vision has been provided by? the four schools and by the Chancellor's Office. We believe that this? infusion of new energy and resources will create and sustain a rich environment for innovative research? and drive the realization of UCSF's full potential to educate and to support the work of clinical and? translational scientists. If so, biomedicine will be advanced and the health of our patients and the? community will benefit.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Mentored Career Development Award (KL2)
Project #
5KL2RR024130-03
Application #
7485631
Study Section
Special Emphasis Panel (ZRR1-CR-3 (01))
Program Officer
Filart, Rosemarie
Project Start
2006-09-30
Project End
2011-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
3
Fiscal Year
2008
Total Cost
$3,805,299
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Wehner, M R; Dalma, N; Landefeld, C et al. (2018) Natural history of lesions suspicious for basal cell carcinoma in older adults in Ikaria, Greece. Br J Dermatol 179:767-768
Thompson, Lisa M; Hengstermann, Mayari; Weinstein, John R et al. (2018) Adoption of Liquefied Petroleum Gas Stoves in Guatemala: A Mixed-Methods Study. Ecohealth 15:745-756
Schaller, Melinda S; Ramirez, Joel L; Gasper, Warren J et al. (2018) Frailty Is Associated with an Increased Risk of Major Adverse Cardiac Events in Patients with Stable Claudication. Ann Vasc Surg 50:38-45
O'Brien, Kieran S; Cotter, Sun Y; Amza, Abdou et al. (2018) Childhood Mortality After Mass Distribution of Azithromycin: A Secondary Analysis of the PRET Cluster-randomized Trial in Niger. Pediatr Infect Dis J 37:1082-1086
Mangurian, Christina; Modlin, Chelsea; Williams, Lindsey et al. (2018) A Doctor is in the House: Stakeholder Focus Groups About Expanded Scope of Practice of Community Psychiatrists. Community Ment Health J 54:507-513
St Helen, Gideon; Shahid, Marian; Chu, Sherman et al. (2018) Impact of e-liquid flavors on e-cigarette vaping behavior. Drug Alcohol Depend 189:42-48
Arya, Shipra; Lee, Sujin; Zahner, Greg J et al. (2018) The association of comorbid depression with mortality and amputation in veterans with peripheral artery disease. J Vasc Surg 68:536-545.e2
Ramirez, Joel L; Drudi, Laura M; Grenon, S Marlene (2018) Review of biologic and behavioral risk factors linking depression and peripheral artery disease. Vasc Med 23:478-488
Cohen, Stephanie E; Sachdev, Darpun; Lee, Sulggi A et al. (2018) Acquisition of tenofovir-susceptible, emtricitabine-resistant HIV despite high adherence to daily pre-exposure prophylaxis: a case report. Lancet HIV :
Singer, Jonathan P; Diamond, Joshua M; Anderson, Michaela R et al. (2018) Frailty phenotypes and mortality after lung transplantation: A prospective cohort study. Am J Transplant 18:1995-2004

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