The goal of the Mayo Clinic CTSA application is to present our vision for the integration and expansion of our? innovative clinical and translational research activities, so that a highly functional academic home for clinical? and translational research is developed at the Mayo Clinic. This new Center for Clinical and Translational? Research (CCTR) will be founded on Mayo's long-standing excellence in and commitment to clinical and? translational research, which includes the support of key infrastructure and a commitment to career? development. To achieve this goal we describe a comprehensive approach to the key elements of the CTSA? RFA and focus on enhancing: 1) Clinical Research Core Resources that provide innovative tools to? investigators; 2) Career Development and Education Programs that prepare the next generation of? investigators; 3) Compliance and Regulatory Affairs Support that ensures patient safety and privacy, and? customer service-oriented approaches to support investigative teams; 4) Community Affairs support to? enhance participation, diversity and community support for clinical and translational research; 5)? Collaboration with Industry and Clinical Practices to translate research discoveries into routine clinical? practice; and 6) Continued and Expanded Institutional Support that includes an """"""""academic home"""""""" for? clinical and translational research. We also propose a consolidated governance plan that incorporates strong? data-driven evaluation of each CCTR element and the program as a whole. In principle, the CTSA program? is consistent with the historical, conceptual and philosophical underpinnings of Mayo Clinic, and in this? application we clearly articulate our vision of how the overarching and transformative goals of the CTSA? program can be met at Mayo. Additionally, we have the """"""""institutional will"""""""" and are culturally empowered to? execute our plan. Thus, Mayo is ready to implement the CTSA program aggressively and rapidly; the Mayo? Clinic CCTR will be a highly functional and successful """"""""flagship"""""""" site for the CTSA program as it emerges? from the NIH Roadmap.? To summarize, the Mayo Clinic Center for Clinical and Translational Research (CCTR) will bring? together all the resources of the five schools within the Mayo Clinic College of Medicine, and more than 100? years of scientific and medical research expertise, to discover innovative new methods that will speed the? translation of research results into therapies, tools and patient care practices that impact all members of our? local and national communities. This vision is entirely consistent with the stated mission of the Mayo Clinic to? provide the best care to every patient every day.through integrated clinical practice, education and research.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Mentored Career Development Award (KL2)
Project #
5KL2RR024151-03
Application #
7495990
Study Section
Special Emphasis Panel (ZRR1-CR-A (01))
Program Officer
Rosenblum, Daniel
Project Start
2006-09-30
Project End
2011-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
3
Fiscal Year
2008
Total Cost
$3,096,764
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Gawad, Noha Abdel; Mohamed, Khalid; Choi, Doo-Sup et al. (2018) No differences in manic-like behaviors between voluntary ethanol and water drinking in Lateral Hypothalamic Kindled (LHK) alcohol preferring rats. Psychiatry Res 261:186-189
Mendis, Shehara M; Vasoo, Shawn; Johnston, Brian D et al. (2018) Clinical and Molecular Correlates of Escherichia coli Bloodstream Infection from Two Geographically Diverse Centers in Rochester, Minnesota, and Singapore. Antimicrob Agents Chemother 62:
De Jager, Philip L; Ma, Yiyi; McCabe, Cristin et al. (2018) A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research. Sci Data 5:180142
Luzum, J A; Pakyz, R E; Elsey, A R et al. (2017) The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems. Clin Pharmacol Ther 102:502-510
Yaghjyan, Lusine; Stoll, Ethan; Ghosh, Karthik et al. (2017) Tissue-based associations of mammographic breast density with breast stem cell markers. Breast Cancer Res 19:100
Singh, Jasvinder A; Noorbaloochi, Siamak; Knutson, Keith L (2017) Cytokine and neuropeptide levels are associated with pain relief in patients with chronically painful total knee arthroplasty: a pilot study. BMC Musculoskelet Disord 18:17
Johnson, Matthew L; Distelmaier, Klaus; Lanza, Ian R et al. (2016) Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults. Diabetes 65:74-84
Yoshino, Satoshi; Cilluffo, Rebecca; Prasad, Megha et al. (2016) Sex-Specific Genetic Variants are Associated With Coronary Endothelial Dysfunction. J Am Heart Assoc 5:e002544
Cheville, Andrea L; Murthy, Naveen S; Basford, Jeffrey R et al. (2016) Imaging and Clinical Characteristics Predict Near-Term Disablement From Bone Metastases: Implications for Rehabilitation. Arch Phys Med Rehabil 97:53-60
Hohman, Timothy J; Cooke-Bailey, Jessica N; Reitz, Christiane et al. (2016) Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement 12:233-43

Showing the most recent 10 out of 262 publications