In just over four years, the Weill Cornell Medical Center Clinical and Translational Science Center (CTSC) has established a strong and highly effective clinical and translational science infrastructure spanning six diverse partners, each a center of excellence: Memorial Sloan-Kettering Cancer Center; Hospital for Special Surgery; Hunter College School of Nursing, Hunter College Gene Center-a Research Center for Minority Institutions (RCMI); Cornell University Cooperative Extension; and Cornell University, Ithaca. The mission of the CTSC in continuation is to leverage the resources and expertise of this rich multi-institutional partnership to create new interdisciplinary teams and support cutting-edge research from bench to bedside to community to health care practice. The proposed grant adds a new partner, the Animal Medical Center a few blocks from WCMC, to increase collaboration with Cornell University College of Veterinary Medicine. Jointly, they bring a new dimension to our CTSC research and their expertise in small animals will enhance pre-clinical research in the area of drug discovery and device development. Built on the accomplishments achieved during the initial funding period, the strategic plans for the next five years are geared to rapidly advance translational science discoveries by: 1) Enhancing the Drug Discovery Pipeline; 2) Increasing the Breadth of Research Resources; 3) Adding New Expertise and Training Programs; and 4) Enhancing Community Engagement and Dissemination. Moving forward, the anticipated benefits of fostering Innovation through Collaboration during the next funding period include: 1) Further generation of novel ideas leading to drug development and medical devices which benefit patient care; 2) Increased collaborative efforts with partners and industry, to facilitate research to improve the general health of the public; 3) Enhanced clinical translational (C/T) educational programs in comparative effectiveness research, global health and health information technology; 4) Enhanced community engagement; 5) Increased centralization of C/T research, education, infrastructure, and databases; and 6) Enhanced evaluation and tracking of CTSC programs.

Public Health Relevance

The broad research support infrastructure of the CTSC and its programs to foster interactions among basic scientists, clinicians and community practitioners are key to the rapid translation of basic science discoveries into effective clinical practice. Our CTSC is distinct in the heterogeneity of its component institutions, providing unparalleled opportunities for collaboration and training in all areas of biomedical sciences.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Mentored Career Development Award (KL2)
Project #
5KL2TR000458-09
Application #
8909234
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Sufian, Meryl
Project Start
2007-09-17
Project End
2016-05-31
Budget Start
2015-06-01
Budget End
2016-05-31
Support Year
9
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Navi, Babak B; Reiner, Anne S; Kamel, Hooman et al. (2018) Reply: Arterial Thromboembolism in Non-Hodgkin Lymphoma, as the Presentation of Occult Cancer, and With Cancer Therapies. J Am Coll Cardiol 71:260-262
Harrington, John S; Schenck, Edward J; Oromendia, Clara et al. (2018) Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials. J Crit Care 47:49-54
Raghunathan, Nirupa Jaya; Benedict, Catherine; Thom, Bridgette et al. (2018) Young Adult Female Cancer Survivors' Concerns About Future Children's Health and Genetic Risk. J Adolesc Young Adult Oncol 7:125-129
Isa, Flonza; Collins, Sean; Lee, Myung Hee et al. (2018) Mass Spectrometric Identification of Urinary Biomarkers of Pulmonary Tuberculosis. EBioMedicine 31:157-165
Navi, Babak B; Marshall, Randolph S; Bobrow, Dylan et al. (2018) Enoxaparin vs Aspirin in Patients With Cancer and Ischemic Stroke: The TEACH Pilot Randomized Clinical Trial. JAMA Neurol 75:379-381
Ma, Kevin C; Schenck, Edward J; Pabon, Maria A et al. (2018) The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness. Am J Respir Crit Care Med 197:300-309
Faltas, Bishoy M; Gennarelli, Renee L; Elkin, Elena et al. (2018) Metastasectomy in older adults with urothelial carcinoma: Population-based analysis of use and outcomes. Urol Oncol 36:9.e11-9.e17
Schenck, Edward J; Ma, Kevin C; Murthy, Santosh B et al. (2018) Danger Signals in the ICU. Crit Care Med 46:791-798
Finn, Caitlin; Hung, Peter; Patel, Praneil et al. (2018) Relationship Between Visceral Infarction and Ischemic Stroke Subtype. Stroke 49:727-729
Chen, Monica Lin; Gupta, Ajay; Chatterjee, Abhinaba et al. (2018) Association Between Unruptured Intracranial Aneurysms and Downstream Stroke. Stroke 49:2029-2033

Showing the most recent 10 out of 100 publications