The Wake Forest (WF) Clinical and Translational Science Institute (CTSI) prepares and expands the translational workforce in support of WF?s goal to become a leading Academic Learning Health System (aLHS). During the first 3 years of CTSA funding, we achieved great success in advancing WF?s educational goals by: selecting and supporting 5 outstanding Scholars; implementing an innovative team-mentoring program to augment traditional dyadic mentoring; refining our Translational Research Academy, a venue to build translational research competencies and foster team-based multidisciplinary approaches; bringing together all research education stakeholders to identify gaps and synergies that strengthen research training across the institution; establishing meaningful partnerships with regional KL2 Programs; and completing regular, rigorous evaluations of the Program. We will build on these achievements over the next 5 years to develop academic leaders prepared to conduct research in an evolving aLHS environment. We will: 1) Administer an effective Early-Career Faculty Mentored Career Development Program, fully integrated with the WF CTSI?s other components and aligned with translational research education initiatives in the CTSA network; 2) Identify, recruit, and support a diverse group of promising early-career faculty KL2 Scholars through individual development plans and resources to facilitate their success in an innovative team-mentoring paradigm; and 3) Develop the online Translational Research Education Enhancement (Learning TREE) tool: a one-stop customizable portal to access, manage, and evaluate educational offerings to build and support Individual Development Plans and self-directed curricula in translational research. We will maintain elements of the Program rated highly by Scholars, including peer networking opportunities; regular, consistent interactions with senior faculty; connections to personal Research Navigators, including a board-certified medical editor; and preferred access to CTSI services. In addition, we will incorporate Scholar feedback to enhance the program. We will strengthen our efforts to build diversity in our KL2 program, which also will enhance the environment for all URM early-career researchers at Wake Forest. We will continue to deepen and refine our efforts at building multidisciplinary and team-based perspectives, including a visiting Scholars program, training in team formation, and participation in team formation activities. We will augment the research productivity of our Scholars and improve their business and management skills. The KL2 program will collaborate with other CTSI programs to build tools and curricula, including the novel Learning TREE. With CTSA support, the WF KL2 Program will continue to select, recruit, and nurture promising early-career faculty with a passion for translational research, in a program that is both individualized and comprehensive. Our vision is that these Scholars will help catalyze team science activities and become aLHS leaders who engineer WF?s future growth and innovation.

Public Health Relevance

The Wake Forest Clinical and Translational Science Institute?s KL2 Program prepares early-career clinical and translational research faculty for academic success and Academic Learning Health System leadership in a rapidly evolving research environment. We select, recruit, and nurture promising early-career faculty with a passion for translational research in a program that is both individualized and comprehensive, under the guidance of multidisciplinary teams of diverse and experienced mentors. Our vision is that these Scholars will help catalyze team science activities and become leaders who engineer growth and innovation in our Academic Learning Health System environment.

National Institute of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
Mentored Career Development Award (KL2)
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Special Emphasis Panel (ZTR1)
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Gopal-Srivastava, Rashmi
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Wake Forest University Health Sciences
Internal Medicine/Medicine
Schools of Medicine
United States
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Callahan, Kathryn E; Lovato, Laura; Miller, Michael E et al. (2018) Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc 66:1927-1933
Haykowsky, Mark J; Nicklas, Barbara J; Brubaker, Peter H et al. (2018) Regional Adipose Distribution and its Relationship to Exercise Intolerance in Older Obese Patients Who Have Heart Failure With Preserved Ejection Fraction. JACC Heart Fail 6:640-649
Millichap, John J; Strowd 3rd, Roy E (2018) Resident & Fellow Rounds. Neurology 90:39-40
Kast, Richard E; Skuli, Nicolas; Cos, Samuel et al. (2017) The ABC7 regimen: a new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy. Breast Cancer (Dove Med Press) 9:495-514
Szuch, Eliza; Caress, James B; Paudyal, Bandhu et al. (2017) Head drop after botox: Electrodiagnostic evaluation of iatrogenic botulinum toxicity. Clin Neurol Neurosurg 156:1-3
Kuchinad, Kamini E; Strowd, Roy; Evans, Anne et al. (2017) End of life care for glioblastoma patients at a large academic cancer center. J Neurooncol 134:75-81
Strowd, Roy E; McBride, Allison; Goforth, Jon et al. (2017) Educational priorities of students in the entrustable professional activity era. Clin Teach :
Prabhakaran, Jaya; Zanderigo, Francesca; Sai, Kiran Kumar Solingapuram et al. (2017) Radiosynthesis and in Vivo Evaluation of [11C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain. ACS Chem Neurosci 8:1697-1703
Schreck, Karisa C; Lwin, MonYi; Strowd, Roy E et al. (2017) Effect of ketogenic diets on leukocyte counts in patients with epilepsy. Nutr Neurosci :1-6
Solingapuram Sai, Kiran Kumar; Das, Bhaskar C; Sattiraju, Anirudh et al. (2017) Radiolabeling and initial biological evaluation of [18F]KBM-1 for imaging RAR-? receptors in neuroblastoma. Bioorg Med Chem Lett 27:1425-1427

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