NUCATS began our KL2 program in 2008, along with numerous other programs to support K scholars across our hub. The 25 KL2 scholars who have participated in the program include 11 MDs, 8 MD/PhDs and 7 PhDs, whose research areas span laboratory-based translational discovery, outcome measures testing, genomic translation, clinical trials, and community-level interventions. As of fall 2018, 21 KL2 scholars have completed the program. The progress of the KL2 program at NU has been outstanding. The scholars' publication and grant records are exceptional. Seventy-five percent (15/21) of those who completed the program have received individual or independent NIH, DHHS, or AHRQ grant support, including 3 K08s, 1 K22, 5 K23s, 12 R01s, 2 R03s, 1 R18, 1 R21, and 1 R34 Furthermore, 85% of those who have completed the program received NIH support as a PI or a significant contributor, while 90% have received some form of NIH or non-NIH grant support. Subsequent to their appointment periods, our scholars have received a combined total of over $45 million in direct research grants as PIs. Approximately 704 publications (mean 34), as author or co-author, have been attributed to the 21 scholars who have completed the program, after they joined the KL2 program. These data document a strong and sustained impact of the NUCATS KL2 Career Development Program on the CTS community. Closely aligned with the overall goals of NUCATS, we will now build on our outstanding legacy and enhance our impact through three initiatives, by: refining our proven programs, which are based on robust mentoring teams and designed around the educational needs of individual scholars to provide them with optimal, personalized career development opportunities; providing career development resources including formal courses, peer mentoring and systematic career guidance to scholars across disparate areas of expertise; and integrating collaboration, training and resources for scholars, including opportunities for training in team science and community implementation and dissemination, for research experiences in academia, government and industry, and for interactions with other local CTSAs.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Mentored Career Development Award (KL2)
Project #
2KL2TR001424-05A1
Application #
9938855
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Wilde, David B
Project Start
2015-08-12
Project End
2024-06-30
Budget Start
2019-07-15
Budget End
2020-06-30
Support Year
5
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Lemmer, Alexander; VanWagner, Lisa B; Ganger, Daniel (2018) Assessment of Advanced Liver Fibrosis and the Risk for Hepatic Decompensation in Patients With Congestive Hepatopathy. Hepatology 68:1633-1641
VanWagner, Lisa B; Harinstein, Matthew E; Runo, James R et al. (2018) Multidisciplinary approach to cardiac and pulmonary vascular disease risk assessment in liver transplantation: An evaluation of the evidence and consensus recommendations. Am J Transplant 18:30-42
VanWagner, Lisa B (2018) A simple clinical calculator for assessing cardiac event risk in liver transplant candidates: The cardiovascular risk in orthotopic liver transplantation score. Clin Liver Dis (Hoboken) 11:145-148
Liotta, Eric Michael; Romanova, Anna L; Lizza, Bryan D et al. (2018) Osmotic Shifts, Cerebral Edema, and Neurologic Deterioration in Severe Hepatic Encephalopathy. Crit Care Med 46:280-289
VanWagner, Lisa B; Ning, Hongyan; Allen, Norrina B et al. (2018) Twenty-five-year trajectories of insulin resistance and pancreatic ?-cell response and diabetes risk in nonalcoholic fatty liver disease. Liver Int 38:2069-2081
Rydzewski, Nicholas R; Lesniak, Maciej S; Chandler, James P et al. (2018) Gross total resection and adjuvant radiotherapy most significant predictors of improved survival in patients with atypical meningioma. Cancer 124:734-742
Liotta, Eric Michael; Ganger, Daniel; Ladner, Daniela P et al. (2018) The authors reply. Crit Care Med 46:e728-e729
Pereira, Deepika; Liotta, Eric; Mahmoud, Ahmed A (2018) The Use of Kcentra® in the Reversal of Coagulopathy of Chronic Liver Disease. J Pharm Pract 31:120-125
Naidech, Andrew M; Beaumont, Jennifer; Muldoon, Kathryn et al. (2018) Prophylactic Seizure Medication and Health-Related Quality of Life After Intracerebral Hemorrhage. Crit Care Med 46:1480-1485
VanWagner, Lisa B; Montag, Samantha; Zhao, Lihui et al. (2018) Cardiovascular Disease Outcomes Related to Early Stage Renal Impairment After Liver Transplantation. Transplantation 102:1096-1107

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