Tuberculosis is often associated with systemic inflammation (SIRS) manifested by fever, sweats, weakness, decreased appetite, weight loss, and elevation of acute phase reactants. The study will assess whether plasma and urinary concentrations of proinflammatory cytokines and their shed receptors (TNF, IL-1, IL-6, IL-8, IL-10 and P75 receptors of TNF, IL-lra) are elevated in patients with active tuberculosis prior to treatment.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000043-39
Application #
6283439
Study Section
Special Emphasis Panel (ZRR1-GCRC-3 (01))
Project Start
1974-10-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
39
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
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