Substance abuse is a widely recognized health problem in the US, with devasting impact on individuals and families. Many illnesses are due directly to alcohol abuse, rendering alcoholics among the highest cost users of medical care in the country. Blacks suffer disproportionately from substance use-related health and social problems. The high prevalence of substance use in young urban black males increases their risk of death and disability, often from cardiovascular disease, stroke, and renal disease. Substance use is a modifiable risk factor impacting many health outcomes, including high blood pressure (HBP). The need for substance abuse treatmetn as an integral part of HBP care and control has been demonstrated. However, interventin research has not yet addressed this need in this population. The development and evaluation of practical, cost-effective, and culturally sensitive interventins that address the problem of substance abuse in the high risk, vulnerable population of underserved hypertensive black males is imperative. The proposed dissertation study is designed as a randomized clinical trial with two parallel arms to test the effect of a brief substance abuse intervention on: 1. completion of referral to substance abuse treatment services; 2. substance use patterns; and 3. level of BP. Substance abusing black men with HPB will be randomized to receive either 1. HPB care by a nurse practitioner or 2. the brief intervention for substance abuse in addition to HBP care provided by a nurse practitioner. The brief intervention which is developed to enhance self-efficacy and readiness to change substance use will be developed and tested in a two phase project. The first phase will involve conducting focus groups and pilot testing to refine the brief intervention. In the second phase, the following hypotheses will be tested: 1. Increase self-efficacy and advance along the continuum of readiness to change substance use behaviors. 2. Increase completion of referral to substance abuse treatment services; 3. Increase utilizatoin of substance abuse treatment services; 4. Decrease substance use; and 5. Decrease level of BP. This study is significant because: 1. It specifically targets the vulnerable, underserved population of Black men with substance use-related problems who are at high risk for premature morbidity and mortality; 2. It evaluates a state-of-the-art nursing intervention that the applicant hypothesizes to be effective in improving an important health outcome in this disproportionately affected group; 3. Preliminary work in the parent study confirms the need for the proposed dissertation research, and 4. It takes advantage of the parent grant which provides extraordinary resources for dissertation level research.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000052-39
Application #
6412493
Study Section
Special Emphasis Panel (ZRR1)
Project Start
1975-10-01
Project End
2004-11-30
Budget Start
Budget End
Support Year
39
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Al-Sofiani, Mohammed E; Yanek, Lisa R; Faraday, Nauder et al. (2018) Diabetes and Platelet Response to Low-Dose Aspirin. J Clin Endocrinol Metab 103:4599-4608
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Grams, Morgan E; Sang, Yingying; Ballew, Shoshana H et al. (2018) Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. Kidney Int 93:1442-1451
Yanik, Elizabeth L; Hernández-Ramírez, Raúl U; Qin, Li et al. (2018) Brief Report: Cutaneous Melanoma Risk Among People With HIV in the United States and Canada. J Acquir Immune Defic Syndr 78:499-504
Aboud, Katherine S; Barquero, Laura A; Cutting, Laurie E (2018) Prefrontal mediation of the reading network predicts intervention response in dyslexia. Cortex 101:96-106
Kattan, Meyer; Bacharier, Leonard B; O'Connor, George T et al. (2018) Spirometry and Impulse Oscillometry in Preschool Children: Acceptability and Relationship to Maternal Smoking in Pregnancy. J Allergy Clin Immunol Pract 6:1596-1603.e6
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Salemi, Parissa; Skalamera Olson, Julie M; Dickson, Lauren E et al. (2018) Ossifications in Albright Hereditary Osteodystrophy: Role of Genotype, Inheritance, Sex, Age, Hormonal Status, and BMI. J Clin Endocrinol Metab 103:158-168
Robert Braši?, James; Mari, Zoltan; Lerner, Alicja et al. (2018) Remission of Gilles de la Tourette Syndrome after Heat-Induced Dehydration. Int J Phys Med Rehabil 6:
Altman, Matthew C; Whalen, Elizabeth; Togias, Alkis et al. (2018) Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. J Allergy Clin Immunol 142:1856-1866

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