Anabolic modulatory and catabolic-inducing factors produced by osteoarthritis synovial tissue as relates to their effect on cartilage metabolism are being studied. The specificity of growth factor/cytokine production is being analyzed by bioassay, radioimmunoassay, Western blotting and by hybridization studies using specific cDNA probes.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
General Clinical Research Centers Program (M01)
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University of Cincinnati
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