This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a randomized Phase IV study of immediate versus deferred antiretroviral therapy in antiretroviral-naive subjects (or distant minimal treatment) with advanced immunodeficiency syndrome who are presenting with acute AIDS-related opportunistic infection (OIs) or bacterial pneumonia and CD4+ count < 200 cells/mm3 for which there are recognized effective antimicrobial therapies available.
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