The primary endpoint of this randomized trial will compare survival with preservation of the larynx using two arms: induction chemotherapy followed by RT versus concomitant treatment with chemotherapy and radiation. The following outcomes will be assessed: length of disease free survival, length of overall survival, evaluation of tumor response, patterns of relapse, incidence of second primary tumors, incidence of adverse effects, concomitant morbidity of neck dissection and/or laryngeal salvage surgery and quality of life.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
37
Fiscal Year
1998
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
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